Robert L Potter

US Patent:

6984526, Jan 10, 2006

Filed:

May 21, 2001

Appl. No.:

09/861781

Inventors:

Luis Humberto Garcia-Rubio - Temple Terrace FL, US
Robert Potter - Tampa FL, US
German Leparc - Tampa FL, US
Sharyn Orton - New Port Richey FL, US
Yvette Mattley - Tampa FL, US
Christina Bacon - Tampa FL, US

Assignee:

University of South Florida - Tampa FL

International Classification:

G01N 21/62

US Classification:

436171, 435 2, 435 3, 435 5, 435 724, 436 10, 436 16, 436 63, 436175, 356 39, 356426, 356427, 422 73

Abstract:

A method and apparatus for characterizing the type of a blood sample and a variety of blood components are provided wherein a transmission spectrum of the sample is collected over a predetermined wavelength range. For blood typing, this spectrum is then compared with a set of control spectra collected from control blood samples having known blood types, from which the type of the blood sample can be determined. Further methods and apparatus are provided for determining the viability of and for cross matching a platelet unit. Additional method and apparatus permit analysis of the sample for the presence of a contaminant. Particles can also be counted in the sample, even when present in low concentrations, including white blood cell.

US Patent:

7691642, Apr 6, 2010

Filed:

Nov 23, 2005

Appl. No.:

11/164466

Inventors:

Luis Humberto Garcia-Rubio - Temple Terrace FL, US
Robert Potter - Tampa FL, US
German Leparc - Tampa FL, US
Sharyn Orton - Frederick MD, US
Yvette Mattley - Tampa FL, US
Christina Bacon - Tampa FL, US

Assignee:

University of South Florida - Tampa FL

International Classification:

G01N 33/48

US Classification:

436163, 436 1, 436 2, 436 44, 436 46, 436 50, 436 55, 436 61, 436164, 436166, 436171, 435 2, 435 4, 435374, 4352841, 4352871, 422 58

Abstract:

A method and apparatus for characterizing the type of a blood sample and a variety of blood components are provided wherein a transmission spectrum of the sample is collected over a predetermined wavelength range. For blood typing, this spectrum is then compared with a set of control spectra collected from control blood samples having known blood types, from which the type of the blood sample can be determined. Further methods and apparatus are provided for determining the viability of and for cross matching a platelet unit Additional method and apparatus permit analysis of the sample for the presence of a contaminant, Particles can also be counted in the sample, even when present in low concentrations, including white blood cell.

US Patent:

63300583, Dec 11, 2001

Filed:

Apr 13, 2000

Appl. No.:

9/548569

Inventors:

Luis Humberto Garcia-Rubio - Temple Terrace FL
Smita Narayanan - Tampa FL
German Leparc - Tampa FL
Robert Potter - Tampa FL
Sharyn Orton - Rockville MD

Assignee:

University of South Florida - Tampa FL

International Classification:

G01N 3348
G01N 3353

US Classification:

356 39

Abstract:

A method and apparatus for characterizing the type of a blood sample are provided wherein an optical density spectrum of the sample is collected over a predetermined wavelength range. A reference optical density spectrum is collected over a predetermined wavelength range for a portion of the blood sample diluted in saline. Another portion of the blood sample is then mixed with an antibody corresponding to a known blood type (e. g. , anti-A, anti-B, anti-D antibody). The optical density spectrum is then collected over a predetermined wavelength range for blood diluted with saline and each antibody in saline. The slopes are then calculated over a predetermined wavelength range for each spectrum. A numerical indicator of agglutination is then calculated by dividing the slope of each antibody-treated sample by the slope of the sample in saline. The resulting number is multiplied by 100.

US Patent:

55899323, Dec 31, 1996

Filed:

Feb 8, 1995

Appl. No.:

8/385717

Inventors:

Luis H. Garcia-Rubio - Temple Terrace FL
Manuel Bayona - Lutz FL
Robert Potter - Tampa FL
German Leparc - Tampa FL

Assignee:

University of South Florida - Tampa FL

International Classification:

G01N 3348
A61B 500
G06F 1500

US Classification:

356 39

Abstract:

A method and apparatus for determining the type of a blood sample are provided wherein a turbidity spectrum of the blood sample is collected over a predetermined wavelength range, from which is calculated an extinction spectrum. This extinction spectrum is then compared with a set of control spectra collected from control blood samples having known blood types, from which the type of the blood sample can be determined. A further method is provided for for detecting the presence of a substance in a bodily fluid sample, the substance having a size in the range of generally 0. 5 to 20. mu. m. Exemplary substances that could be of interest to detect include, but are not limited to, hemoglobin, bilirubin, red blood cell antigens, microorganisms, and viruses. This embodiment includes the additional step of deconvoluting the extinction spectrum to obtain a particle size distribution for comparison with a database of control samples.

US Patent:

51282437, Jul 7, 1992

Filed:

Jun 28, 1990

Appl. No.:

7/544890

Inventors:

Robert L. Potter - Tampa FL
Richard L. L. Mansell - Tampa FL

Assignee:

University of South Florida - Tampa FL

International Classification:

G01N 3353
G01N 33537
G01N 33543
A61K 3514

US Classification:

435 792

Abstract:

An immunoassay for the detection of beet sugar adulteration of sugar-containing materials such as fruit juices and fruit juice concentrates utilizes antibodies to proteinaceous components of beet sugar. These proteinaceous components have been found in all samples of beet sugar, tested, regardless of source or degree of refinement; these proteinaceous components have also been found in both crystal and invert sugars.