Roger E Clark

US Patent:

6731180, May 4, 2004

Filed:

Oct 22, 2001

Appl. No.:

10/056958

Inventors:

Roger L. Clark - Windham NH
Joseph V. Adler - New Milford CT
Jacob M. Li - Danbury CT

Assignee:

Deleware Capital Formation Inc. - Wilmington DE

International Classification:

H03B 532

US Classification:

331176, 331 68, 331 69, 331158, 310341, 310343, 310344

Abstract:

The present invention is for a thermally controlled package for oscillators, particularly evacuated miniature surface acoustical wave oscillators (EMSO) devices. In a preferred embodiment the surface acoustical wave device is bonded directly to a heated substrate. The package is evacuated to improve temperature characteristics. A temperature heater, sensor, and control controller are utilized to maintain the internal package temperature above ambient. In one embodiment there is an additional substrate layer that house components that are not sensitive to temperature with interconnects electrically connecting the heated substrate and the additional substrates.

US Patent:

6825734, Nov 30, 2004

Filed:

Nov 13, 2003

Appl. No.:

10/706895

Inventors:

Roger L. Clark - Windham NH

Assignee:

Phasor Technologies Corporation - Windham NH

International Classification:

H03B 518

US Classification:

331 96, 331117 D, 331179, 333219

Abstract:

A transmission line configured as a looped-stub resonator is disclosed, which can be used as a frequency selective element for an oscillator, such as a VCO of a phase locked loop. The transmission line is a fraction of an electrical wavelength, and can be embedded to provide an inner resonant layer of an overall layered structure. The transmission line is formed into a loop or multiple loops and may be terminated with a capacitor, short circuit, or open circuit. In the embedded case, dielectric insulating material can be used to surround the transmission line on top and bottom surfaces as layers. In addition, electrically conducting material layers can be used to surround the dielectric insulating material.

US Patent:

7310024, Dec 18, 2007

Filed:

Feb 25, 2006

Appl. No.:

11/362649

Inventors:

Bryan T. Milliren - Newbury MA, US
Roger L. Clark - Windham NH, US

International Classification:

H03B 5/32
H03B 1/00

US Classification:

331 69, 331176, 331158

Abstract:

A double oven crystal oscillator (DOCXO) is disclosed which is highly stable by incorporating means to reduce the effects of ambient pressure changes on the frequency of the oscillator. The oscillator crystal is mounted in a temperature controlled inner oven to reduce the effects on the frequency stability of the oscillator. The oscillator circuitry and all circuitry associated with the inner oven is mounted in good thermal contact with the inner oven. A Faraday shield at ground potential is placed over the oscillator circuitry to minimize the effects of stray capacitance between the oscillator components and the case wall of the inner oven. The effects of minor deformations in the case walls within the oscillator caused by ambient pressure changes and other factors causing pressure changes are thereby greatly minimized. To further reduce effects on oscillator frequency stability the ovens of the DOCXO are temperature controlled, cases are hermetically sealed, the case walls are rigid, and ovens and cases may be evacuated.

US Patent:

7943622, May 17, 2011

Filed:

Jun 6, 2007

Appl. No.:

11/811010

Inventors:

Roger B. Clark - Lexington MA, US
Daniel Elbaum - Newton MA, US

Assignee:

Cornerstone Therapeutics, Inc. - Cary NC

International Classification:

A61K 31/497
C07D 401/04

US Classification:

5142531, 51425311, 51425312, 544360, 544364

Abstract:

Disclosed are novel piperazine derivatives that act as agonists of the α7 nAChR. Also disclosed are pharmaceutical compositions, methods of treating inflammatory conditions, methods of treating CNS disorders, methods for inhibiting cytokine release from mammalian cells and methods for the preparation of the novel compounds.

US Patent:

8367654, Feb 5, 2013

Filed:

May 7, 2010

Appl. No.:

13/319307

Inventors:

Roger B. Clark - Lexington MA, US
Minsheng He - Watertown MA, US
Louis Plamondon - Belmont MA, US
Xiao-Yi Xiao - San Diego CA, US
Magnus P. Rönn - Melrose MA, US

Assignee:

Tetraphase Pharmaceuticals, Inc. - Watertown MA

International Classification:

A61K 31/397
A61K 31/497
A61K 31/435
C07D 403/02
C07D 221/18
C07D 205/04

US Classification:

51421021, 51425302, 514284, 544361, 546 78, 548950

Abstract:

The present invention is directed to a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. The variables for Structural Formula I are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula I and its therapeutic use.

US Patent:

8451071, May 28, 2013

Filed:

Apr 18, 2011

Appl. No.:

13/088733

Inventors:

Roger L. Clark - Windham NH, US
Mark J. Gugliuzza - Tewksbury MA, US
Benjamin J. Annino - Boston MA, US
Janis R. Cooper - Townsend MA, US

Assignee:

Raytheon Company - Waltham MA

International Classification:

H03L 7/099

US Classification:

331185, 331109, 330285, 330298

Abstract:

An oscillator having: (A) a transistor for producing an oscillating output signal at an output electrode of the transistor. The oscillator includes; (B) a bias circuit for producing a bias signal for the transistor, said bias circuit including an amplifier coupled to the output electrode of the transistor; and (C) a circuit coupled between an output of the amplifier and a control electrode of the transistor, for isolating the bias signal provided by the amplifier from the oscillating signal.

US Patent:

8501716, Aug 6, 2013

Filed:

Aug 9, 2012

Appl. No.:

13/570837

Inventors:

Jingye Zhou - Belmont MA, US
Xiao-Yi Xiao - San Diego CA, US
Louis Plamondon - Belmont MA, US
Diana Katharine Hunt - Cambridge MA, US
Roger B. Clark - Lexington MA, US
Robert B. Zahler - Pennington NJ, US

Assignee:

Tetraphase Pharmaceuticals, Inc. - Watertown MA

International Classification:

A61K 31/65
C07C 237/26

US Classification:

514152, 552205

Abstract:

The present invention is directed to a compound represented by Structural Formula (A):.

US Patent:

8610517, Dec 17, 2013

Filed:

Nov 2, 2010

Appl. No.:

12/917738

Inventors:

Roger L. Clark - Windham NH, US
Seth A. Berman - Marblehead MA, US
Robert E. Kozlowski - Concord MA, US
Gary K. Montress - Westford MA, US

Assignee:

Raytheon Company - Waltham MA

International Classification:

H03H 9/05
H03H 9/205
H03H 9/25
H03B 5/32

US Classification:

333193, 333195, 310313 B, 331107 A

Abstract:

A device, comprising a substrate having opposing first and second surfaces, a first surface acoustic wave resonator disposed on the first surface of the substrate, a second surface acoustic wave resonator disposed on the second surface of the substrate, a first adhesive layer sandwiched between the first surface acoustic wave resonator and the substrate, and a second adhesive layer sandwiched between the second surface acoustic wave resonator.