Roger L Whiting

US Patent:

8277781, Oct 2, 2012

Filed:

Mar 13, 2009

Appl. No.:

12/404250

Inventors:

Roger Whiting - Los Altos CA, US
Ramachandran Thirucote - Atherton CA, US

Assignee:

Luitpold Pharmaceuticals, Inc. - Shirley NY

International Classification:

A61K 9/00
A61M 11/00

US Classification:

424 45, 12820014, 12820322

Abstract:

Disclosed herein are devices and processes for preparing a vial for an intranasal administration of a medicament where the vial comprises reduced oxygen content.

US Patent:

8551454, Oct 8, 2013

Filed:

Mar 11, 2010

Appl. No.:

12/722137

Inventors:

Roger Whiting - Los Altos CA, US
Ramachandran Thirucote - Atherton CA, US

Assignee:

Luitpold Pharmaceuticals, Inc. - Shirley NY

International Classification:

A61K 9/00
A61M 11/00

US Classification:

424 45, 12820014, 12820322

Abstract:

Disclosed herein are vials and devices containing a ketorolac solution for intranasal administration and a head space comprising no more than about 10% v/v oxygen and which vials and devices are stored in an oxygen-impermeable pouch. Also disclosed are processes for preparing the vials and devices.

US Patent:

20060009432, Jan 12, 2006

Filed:

Jul 8, 2005

Appl. No.:

11/177977

Inventors:

Roger Whiting - Los Altos CA, US
Lakshmi Sangameswaran - San Jose CA, US

International Classification:

A61K 31/57

US Classification:

514177000

Abstract:

Ganaxolone (3α-hydroxy-3β-methyl-5β-pregnan-20-one) and 3α-hydroxy-3β-methyl-5β-pregnan-20-one and their physiologically cleavable esters are useful for treating neuropathic pain. Compositions comprising a pharmaceutically acceptable excipient and an appropriate compound, along with methods for preparing the compositions are disclosed. Also disclosed are articles of manufacture wherein the composition is combine with labeling instructions for treating neuropathic pain.

US Patent:

20090042968, Feb 12, 2009

Filed:

Dec 15, 2005

Appl. No.:

11/813763

Inventors:

Roger Whiting - Los Altos CA, US
Ramachandran Thirucote - Atherton CA, US

International Classification:

A61K 31/407
A61P 25/00
A61P 29/00

US Classification:

514413

Abstract:

Therapeutic compositions, particularly sprayable aqueous compositions, comprise ketorolac or a pharmaceutically acceptable salt, in combination with a local anesthetic, such as lidocaine hydrochloride. The compositions are nasally administered to a subject in need thereof to treat pain or inflammation and have the benefit of reduced stinging and improved efficacy, compared to known nasally administered compositions.

US Patent:

20100016402, Jan 21, 2010

Filed:

Jun 12, 2009

Appl. No.:

12/483586

Inventors:

Roger Whiting - Los Altos CA, US
Ramachandran Thirucote - Atherton CA, US

International Classification:

A61K 31/407
A61P 25/06

US Classification:

514413

Abstract:

This invention relates to therapeutic compositions, particularly sprayable aqueous compositions, and unit dose formulations comprise ketorolac or a pharmaceutically acceptable salt, alone or in combination with lidocaine or a pharmaceutically acceptable salt thereof. The compositions are nasally administered to a subject in need thereof to treat pain or inflammation.

US Patent:

20120329849, Dec 27, 2012

Filed:

Sep 4, 2012

Appl. No.:

13/603232

Inventors:

Roger Whiting - Los Altos CA, US
Ramachandran Thirucote - Atherton CA, US

International Classification:

A61K 31/407
A61P 29/00

US Classification:

514413

Abstract:

This invention relates to therapeutic compositions, particularly sprayable aqueous compositions, and unit dose formulations comprise ketorolac or a pharmaceutically acceptable salt, alone or in combination with lidocaine or a pharmaceutically acceptable salt thereof. The compositions are nasally administered to a subject in need thereof to treat pain or inflammation.

US Patent:

20130000634, Jan 3, 2013

Filed:

Sep 13, 2012

Appl. No.:

13/615162

Inventors:

Roger Whiting - Los Altos CA, US
Ramachandran Thirucote - Atherton CA, US

International Classification:

A61M 11/02

US Classification:

12820021

Abstract:

Disclosed herein are devices and processes for preparing a vial for an intranasal administration of a medicament where the vial comprises reduced oxygen content.

US Patent:

52527360, Oct 12, 1993

Filed:

Nov 7, 1991

Appl. No.:

7/789230

Inventors:

Jean C. Pascal - Cachan, FR
Chi-Ho Lee - Palo Alto CA
Brian J. Alps - Linlithgow, GB6
Henri Pinhas - Paris, FR
Roger L. Whiting - Los Altos CA

Assignee:

Syntex Pharmaceuticals, Ltd. - Maidenhead

International Classification:

A61K 31495
C07D40302

US Classification:

544370

Abstract:

Substituted imidazolyl-alkyl-piperazine and diazepine derivatives of Formula A: ##STR1## wherein: R. sup. 1 is aryl, lower alkyl, cycloalkyl or hydrogen; R. sup. 2 is aryl, lower alkyl or hydrogen; R. sup. 3 is lower alkyl, hydroxy, or hydrogen; R. sup. 4 is aryl or hydrogen; R. sup. 5 is aryl or hydrogen; m is two or three; n is zero, one or two, provided that when R. sup. 3 is hydroxy, n is one or two; and q is zero, one, two, or three; and the pharmaceutically acceptable salts thereof, are calcium channel antagonists useful for treating mammals having a variety of disease states, such as stroke, epilepsy, hypertension, angina, migraine, arrhythmia, thrombosis, embolism and also for treatment of spinal injuries.