Dr. Browning graduated from the University of Missouri, Columbia School of Medicine in 1973. He works in Joplin, MO and specializes in Internal Medicine.
Us Patents
Crystallization Process For Ceftazidime Derivative
Ronald C. Browning - Greenwood IN Melvin G. Pleiss - Indianapolis IN
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
C07D49944 A61K 31545
US Classification:
540225
Abstract:
Ceftazidime pentahydrate is obtained in purified crystalline form in a process comprising acidification of an aqueous solution of ceftazidime to about the optimum pH for nucleation of between about 4. 0 and about 4. 7 and maintenance at the optimum pH during crystallization. The crystalline product obtained exhibits enhanced stability toward polymer formation when stressed.