Ronald J. Leonard - Harvard IL Kenneth M. Johnson - Lindenhurst IL
Assignee:
Omnis Surgical Inc. - Deerfield IL
International Classification:
B65H 8108
US Classification:
242 702
Abstract:
A bundle (12) of hollow fiber (34) is formed by winding a length of hollow fiber around a core (38) from an arm (20) that is in a plane at an acute angle with respect to the longitudinal axis of the core and is between opposite ends of the core. Relative rotation is provided between the longitudinal axis of the core and the position of the winding arm. During winding of the hollow fiber around the core, there is an increase in the ratio of (a) the angular velocity of the wind and (b) the relative rotational velocity between the longitudinal axis of the core and the position of the winding arm. In this manner, the void fraction of radially-outward annuli of the wound bundle is less than the void fraction would be if the ratio remained constant.
A system is disclosed for priming an ultrafiltration unit (10) connected to a blood source, without requiring a pump in the blood line. An ultrafiltration unit (10) is provided having an ultrafiltration membrane which separates a blood compartment from an ultrafiltrate compartment, a blood inlet port (12), a blood outlet port (14), a second inlet port (16) communicating with the ultrafiltrate compartment, and an ultrafiltrate outlet port (18). A feedback tube (38) connects the blood outlet port (14) to the second input port (16). Priming solution (36) is introduced to the blood inlet port (12) and a vacuum is applied to the ultrafiltrate outlet port (18). The priming solution (36) is drawn through the blood compartment, through the ultrafiltrate compartment, out the ultrafiltrate outlet port, and to drain.
A hollow fiber separation device such as an oxygenator for blood which comprises a core having a bundle of hollow tubular fibers circumferentially wrapped around the core for separation of materials. A housing encloses the bundle and first and second manifold systems respectively provide separated flow through the bundle in contact with exterior surfaces of the hollow fibers and the bores of the hollow fibers in first and second flow paths. A space extends longitudinally through the bundle exposing open ends of the fibers at opposed sides of the space, regions of the bundle are adjacent to the space being potted to prevent leakage around to the fibers. The second manifold system includes an inlet and outlet conduit, each being in flow communication with the space. Partition means in the space isolates fluid flow between the inlet conduit in one of the opposed sides from fluid flow between the outlet conduit in the other of opposed sides.
Ronald James Leonard - Harvard IL Evelyn Miller - Lindenhurst IL
Assignee:
Baxter Laboratories, Inc. - Deerfield IL
International Classification:
A61M 103 A61M 514
US Classification:
232585R
Abstract:
A variable capacity reservoir assembly for use in a blood oxygenation system which includes a collapsible reservoir and an elongated unitary clamp. The reservoir is of fluid-impermeable flexible material and includes an expandable portion capable of holding a predetermined maximum volume of blood. The reservoir also includes one main blood inlet and one main blood outlet. The clamp is bifurcated and slidably engages the reservoir, preferably between the inlet and the outlet and grasps the expandable portion so as to control the expansion thereof and thereby control its blood holding capacity.
Hydrophobic Diffusion Membranes For Blood Having Wettable Surfaces
Hydrophobic diffusion membranes such as porous polypropylene may be rendered hydrophilic at their surfaces, without losing their valuable characteristics as diffusion membranes, by subjection to a corona discharge or other ionizing condition, preferably in air or a similar oxygen-containing atmosphere.
A system is provided for collecting platelets. Whole blood is removed from a patient 10 and directed to a hemoconcentrator 22 having a blood inlet 24, a blood outlet 26, a blood passage communicating with the blood inlet and blood outlet, an ultrafiltrate outlet 28 and a membrane separating the blood passage from the ultrafiltrate outlet. The blood is passed through the blood passage of the hemoconcentrator while a negative pressure is adapted to the ultrafiltrate outlet. In this manner, the platelets concentrate on the membrane wall. After a selected period of time, the application of the negative pressure is terminated to the ultrafiltrate outlet, and the concentrated platelets from the hemoconcentrator are flushed and directed to a platelet collection container 44. In one embodiment, the flushing solution comprises the patient's blood that is directed via the blood inlet through the blood passage while in another embodiment, the patient's blood is diverted and a saline solution is used as the flush. During the flush, a positive pressure may be applied to the ultrafiltrate outlet of the hemoconcentrator.
Hollow Fiber Bundle Having Transverse Binding Means And Method Of Making Same
Ronald J. Leonard - Harvard IL Kenneth M. Johnson - Lindenhurst IL
Assignee:
Baxter International Inc. - Deerfield IL
International Classification:
B01D 1300
US Classification:
21032174
Abstract:
A mass transfer device (60) includes a hollow fiber bundle (10) comprising a generally cylindrical core (14) having opposed ends, a plurality of layers of hollow fiber (12) that have been wound around the core, and binding means (48a, 48b, 48c), such as double-sided pressure-sensitive tape that have been wound around the layers of hollow fiber in a plurality of longitudinally spaced locations along the core and intermediate the opposite ends of the core for providing longitudinally spaced support means for the hollow fiber bundle. The hollow fiber bundle is enclosed in a housing (62) having an inner wall (80) which defines a generally circular opening for receiving the hollow fiber bundle except that the inner wall adjust a fluid outlet manifold (74) includes an expansion volume (82) for the hollow fibers that are adjacent that fluid outlet manifold. A screen (88) is provided adjacent the fluid outlet manifold to prevent the fibers from migrating too far into the outlet and to provide a controlled expansion.
Ronald J. Leonard - Harvard IL Kenneth M. Johnson - Lindenhurst IL Thomas L. Drehobl - Lindenhurst IL
Assignee:
Baxter Travenol Laboratories, Inc. - Deerfield IL
International Classification:
A61M 118 A61M 136 B01D 1301 F28F 108
US Classification:
422 46
Abstract:
A heat exchanger (38) is provided which may be used in a mass transfer device (20), such asn an oxygenator or a dialyzer. The heat exchanger comprises a core (40) formed of a corrugated metal having a high thermal conductivity. Each of the corrugations of the core comprises substantially parallel side walls (70, 72). A first fluid, such as blood, is introduced onto the outside of the core. A second fluid, such as water, is introduced into the inside of the core. The first and second fluids will be in heat exchange relationship with each other and the flow of the fluids is substantially uniform resulting from the substantially parallel side walls of the corrugations. The core is formed by providing a flexible metalhose, annealing the flexible metal hose, compressing the annealed hose and expanding the compressed hose to a length that is substantially less than its original length but greater than its length during compression.