Ronald L Morton

US Patent:

20040053425, Mar 18, 2004

Filed:

May 6, 2003

Appl. No.:

10/430509

Inventors:

Richard Link - Pikesville MD, US
Ronald Morton - Richmond TX, US
Brian Miles - Houston TX, US
Michael Simon - Houston TX, US

Assignee:

Baylor College of Medicine

International Classification:

G01N033/553

US Classification:

436/526000

Abstract:

Custom-engineered glucose oxidase fusion proteins, prepared by recombinant DNA techniques, are employed in a chip-based amperometric immunosensor. This on-chip assay provides quantitative measurement of analyte concentration in any fluid, including all body fluids. The system is designed to facilitate ease in swapping of molecular recognition components and can be rapidly adapted to measure the concentration of any peptide or protein for which a monoclonal antibody is available.

US Patent:

20040072263, Apr 15, 2004

Filed:

Apr 21, 2003

Appl. No.:

10/419438

Inventors:

Richard Link - Pikesville MD, US
Ronald Morton - Richmond TX, US
Brian Miles - Houston TX, US
Michael Simon - Houston TX, US

Assignee:

Baylor College of Medicine

International Classification:

G01N033/53
C12M001/34

US Classification:

435/007500, 435/287200

Abstract:

Custom-engineered glucose oxidase fusion proteins, prepared by recombinant DNA techniques, are employed in a chip-based amperometric immunosensor. This on-chip assay provides quantitative measurement of analyte concentration in any fluid, including all body fluids. The system is designed to facilitate ease in swapping of molecular recognition components and can be rapidly adapted to measure the concentration of any peptide or protein for which a monoclonal antibody is available.