Saint Louis University School of Medicine University · University Department of Medicine · College/University · College/University Library · General Hospital · Medical Doctor's Office
1402 S Grand Blvd, Saint Louis, MO 63104 1221 S Grand Blvd, Saint Louis, MO 63104 1755 S Grand Blvd, Saint Louis, MO 63104 (314)9776195, (314)5778760, (314)9778730, (314)2685589
Nicholas E. S. Sibinga - Chappaqua NY, US Rong Hou - Fenton MO, US
Assignee:
Albert Einstein College of Medicine of Yeshiva University - Bronx NY
International Classification:
A61K 38/16 C07K 14/00
US Classification:
514 12, 530350
Abstract:
Provided is an extracellular domain of a mammalian Fat1 (Fat1). Also provided is an intracellular domain of a mammalian Fat1 (Fat1). Additionally provided is a vector comprising a nucleic acid sequence encoding the Fat1. A vector comprising a nucleic acid sequence encoding the Fat1is further provided. Also, a vascular stent coated with the Fat1is provided. Further provided is a vascular stent coated with a Fat1 ligand that activates Fat1. A method of treating a patient at risk for restenosis of a blood vessel is additionally provided. Further, methods of treating an injured blood vessel in a patient is provided. A method of treating a patient at risk for restenosis of a blood vessel or having an injured blood vessel is also provided.
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