Rong Sen Li

US Patent:

8007790, Aug 30, 2011

Filed:

Oct 2, 2007

Appl. No.:

11/906600

Inventors:

Rong Li - Kansas City MO, US
Xiaogang Li - Prairie Village KS, US

Assignee:

Stowers Institute for Medical Research - Kansas City MO

International Classification:

A61K 39/395
A61K 39/00
A61K 38/00
C07K 16/24

US Classification:

4241301, 4241331, 4241351, 4241411, 4241451, 514 11

Abstract:

The present invention is directed to methods of treating or ameliorating an effect of a polycystic disease. More particularly, the methods include administering to a patient in need thereof an amount of a modulator of a tumor necrosis factor (TNF) pathway, which is sufficient to treat or ameliorate an effect of a polycystic disease. Methods of treating or ameliorating an effect of a polycystic kidney disease (PKD) are also provided. Methods are also provided for identifying a candidate compound that may be effective to treat or ameliorate an effect of a polycystic disease or to increase polycystin-2 (PC2) function or decrease Rab11-Family of Interacting Protein2 (FIP2) function. Further provided are methods for identifying a patient having, or who is at risk for developing, a polycystic disease or who would benefit from treatment with a TNF-alpha inhibitor.

US Patent:

20080207711, Aug 28, 2008

Filed:

Feb 28, 2008

Appl. No.:

12/072740

Inventors:

Rong Li - Kansas City MO, US
Xiaogang Li - Prairie Village KS, US

International Classification:

A61K 31/425

US Classification:

514369

Abstract:

Described herein is a method of treating an ID2-related disorder comprising administering to a patient in need thereof an ID2 inhibitor or derivative thereof.

US Patent:

20120122787, May 17, 2012

Filed:

Jul 9, 2010

Appl. No.:

13/382978

Inventors:

Rong Li - Kansas City MO, US

International Classification:

A61K 31/165
A61K 31/19
A61P 13/12
A61K 31/18
A61K 38/12
A61K 31/357
A61K 31/47
A61K 31/167
A61K 31/426

US Classification:

514 154, 514619, 514616, 514557, 514370, 514465, 514311, 514603, 514604

Abstract:

The present invention is directed to, inter alia, methods of treating or ameliorating an effect of a polycystic disease. This method include administering to a patient in need thereof an amount of a modulator of a histone deacetylase (HDAC) path-way, which is sufficient to treat or ameliorate an effect of a polycystic disease, particularly a polycystic kidney disease.

US Patent:

56208499, Apr 15, 1997

Filed:

Sep 23, 1994

Appl. No.:

8/311406

Inventors:

Michael R. Botchan - Kensington CA
Liu Yang - Berkeley CA
Rong Li - El Cerrito CA
Ian J. Mohr - Berkeley CA
Robin Clark - Oakland CA

Assignee:

Cetus Corporation - Emeryville CA
The Regents of the University of California - Oakland CA

International Classification:

C12Q 168
C12N 700
A61K 3843
C07K 200

US Classification:

435 6

Abstract:

Compositions and methods for identifying inhibitors of papilloma virus replication are described consisting of soluble cellular extracts supplemented with purified viral E1 and E2 proteins.

US Patent:

20230098709, Mar 30, 2023

Filed:

Dec 5, 2022

Appl. No.:

18/074675

Inventors:

- Wallingford CT, US
Hai Qun Hong - Jiangxi, CN
Robert L. Romerein - Ontario, CA
Rong Hui Li - Brooklyn NY, US

International Classification:

H04N 7/10
H04L 12/64
H04L 12/00
H04L 12/28
H04L 12/66

Abstract:

A Multimedia over Coax Alliance (MoCA) gateway splitter that includes a directional coupler (including a first transmission path and a second transmission path), a gateway port and a cable television (CATV) input port each electrically connected to the first transmission path, and a MoCA port electrically connected to the second transmission path such that the MoCA port is isolated from the CATV input port and coupled to the gateway port. Multiple MoCA ports may be electrically connected to the second transmission path (e.g., via a resistive splitter). The second transmission path may be electrically connected to ground. The MoCA gateway splitter may include multiple (e.g., two or three) gateway ports, each electrically connected to the CATV input port via a directional coupler (and, e.g., one or more hybrid splitters). In those embodiments, each directional coupler may be electrically connected to the MoCA port(s), for example, via a common microstrip node.

US Patent:

20230017123, Jan 19, 2023

Filed:

Jul 14, 2022

Appl. No.:

17/864821

Inventors:

- Wallingford CT, US
Robert L. ROMEREIN - Peterborough, CA
Rong Hui LI - Brooklyn NY, US
Hai Qun HONG - Jiangxi, CN

International Classification:

H04W 48/10

Abstract:

A provider equipment identification (ID) device includes a provider equipment with a plurality of output ports and an ID beacon device. The provider equipment is configured to perform a signal processing operation on an input signal and deliver an output signal to one or more of the output ports. The ID beacon device is coupled to the provider equipment. The ID beacon device is configured to output at least one pilot beacon signal which is receivable by each of the output ports to electrically excite each of the output ports such that the at least one pilot beacon signal is introduced in the output signal to generate an altered output signal capable of identifying the provider equipment.

US Patent:

20210227174, Jul 22, 2021

Filed:

Feb 2, 2021

Appl. No.:

17/165469

Inventors:

- Wallingford CT, US
Hai Qun Hong - Jiangxi, CN
Robert L. Romerein - Ontario, CA
Rong Hui Li - Brooklyn NY, US

International Classification:

H04N 7/10
H04L 12/28
H04L 12/64
H04L 12/00

Abstract:

A Multimedia over Coax Alliance (MoCA) gateway splitter that includes a directional coupler (including a first transmission path and a second transmission path), a gateway port and a cable television (CATV) input port each electrically connected to the first transmission path, and a MoCA port electrically connected to the second transmission path such that the MoCA port is isolated from the CATV input port and coupled to the gateway port. Multiple MoCA ports may be electrically connected to the second transmission path (e.g., via a resistive splitter). The second transmission path may be electrically connected to ground. The MoCA gateway splitter may include multiple (e.g., two or three) gateway ports, each electrically connected to the CATV input port via a directional coupler (and, e.g., one or more hybrid splitters). In those embodiments, each directional coupler may be electrically connected to the MoCA port(s), for example, via a common microstrip node.

US Patent:

20210136321, May 6, 2021

Filed:

Jun 24, 2020

Appl. No.:

16/910800

Inventors:

- Wallingford CT, US
Robert L. Romerein - Ontario, CA
Rong Hui Li - Brooklyn NY, US
Hai Qun Hong - Jiangxi, CN

International Classification:

H04N 7/10

Abstract:

A Multimedia over Coax Alliance (MoCA) gateway splitter that includes a directional coupler (including a first transmission path and a second transmission path), a gateway port and a cable television (CATV) input port each electrically connected to the first transmission path, and a MoCA port electrically connected to the second transmission path such that the MoCA port is isolated from the CATV input port and coupled to the gateway port. Multiple MoCA ports may be electrically connected to the second transmission path (e.g., via a resistive splitter). The second transmission path may be electrically connected to ground. The MoCA gateway splitter may include multiple (e.g., two or three) gateway ports, each electrically connected to the CATV input port via a directional coupler (and, e.g., one or more hybrid splitters). In those embodiments, each directional coupler may be electrically connected to the MoCA port(s), for example, via a common microstrip node.