- Austin TX, US - Washington DC, US Hui DENG - Houston TX, US Xiujie SUN - Washington DC, US Rong LI - Washington DC, US
International Classification:
C07K 16/28 C12N 15/63 A61P 35/00
Abstract:
The present disclosure relates to antibodies binding to tumor discoidin domain receptor 1 (DDR1) and the uses of the antibodies in detecting and treating cancer. Thus, in one aspect, the present disclosure provides an isolated monoclonal antibody or an antigen-binding fragment thereof that binds specifically to DDR1. In certain embodiments, the antibody or antigen-binding fragment, when bound to DDR1, modulates the activity of DDR1, i.e., suppresses DDR1.
Darleen Thorpe (1961-1965), Marla Kramer (1962-1966), pat obrien (1980-1984), rong li (2003-2007), Aaron Erdenberger (1988-1992), Ann Burlingame (1978-1982)