Dan R. Littman - New York NY, US Hongkui Deng - Worcester MA, US Wilfried Ellmeier - New York NY, US Nathaniel R. Landau - New York NY, US Rong Liu - New York NY, US
Entry of HIV-1 into target cells requires cell surface CD4 as well as additional host cell cofactors. A cofactor required for infection with virus adapted for growth in transformed T cell lines was recently identified and named fusin. Fusin, however, does not promote entry of macrophage-tropic viruses that are believed to be the key pathogenic strains in vivo. It has now been determined that the principal cofactor for entry mediated by the envelope glycoproteins of primary macrophage-tropic strains of HIV-1 is CC-CKR5, a receptor for the β-chemokines RANTES, MIP-1α, and MIP-1β.
Optical System For A Digital Light Projection System Including Optical Concentrator Elements Having Reflective Aperture Elements
James F. Shanley - Westborough MA, US Rong Liu - Miami FL, US
Assignee:
Scram Technologies, Inc. - Dunkirk MD
International Classification:
G02B 27/10
US Classification:
359629
Abstract:
An optical system for a digital light projection system is provided. The optical system comprises a plurality of LED arrays, wherein each LED array comprises a plurality of LEDs. The optical system also comprises an optical concentrator element positioned substantially adjacent to each of the LED arrays, wherein each concentrator element reflects light emitted from the plurality of LEDs within the corresponding LED array. The optical system preferably further comprises a reflective aperture element positioned substantially adjacent to the output surface of each concentrator element. The aperture element includes a reflective surface and an aperture defined by the reflective surface. The reflective surface faces the output surface of each corresponding concentrator element to thereby ultimately provide substantially uniform light which is projected through the aperture.
Low Pass Filter Incorporating Coupled Inductors To Enhance Stop Band Attenuation
Wenjiang Zeng - Sunnyvale CA, US Rong Liu - Fremont CA, US Yupeng Chen - Sunnyvale CA, US Wang-Chang Albert Gu - Longwood FL, US
Assignee:
California Micro Devices - Milpitas CA
International Classification:
H03H 7/00
US Classification:
333176, 333167
Abstract:
The present invention relates to a low pass filter incorporating coupled inductors to enhance stop band attenuation. In one embodiment, the coupled inductors are provided along with various capacitors to provide for superior performance within a smaller surface area of a semiconductor or ceramic integrated device. In a further specific embodiment, the capacitors are formed on an integrated device within an area on which entirely intertwined inductors are formed. In another embodiment, at least one further pair of coupled inductors is included to create additional frequency attenuation notches, as well as a wide stop-band.
Ultraviolet Light-Emitting Diode Exposure Apparatus For Microfabrication
Rong Liu - Pleasanton CA, US Evan Palmer - Mountain View CA, US
Assignee:
Optical Associates, Inc. - San Jose CA
International Classification:
G03B 27/32 G03B 27/54
US Classification:
355 67, 355 77
Abstract:
An exposure apparatus for use in optical lithography can include a holder and a plurality of UV-LED modules carried by the holder and disposed in an array. A respective plurality of collimating lenses can be disposed in an array corresponding to the array of UV-LED modules. The plurality of UV-LED modules and the respective plurality of collimating lenses can provide a respective plurality of distinct beams of UV light. The plurality of collimating lenses may be spaced from the plurality of UV-LED modules and spaced from the exposure plane and have an optical configuration providing a composite beam of UV light formed from the plurality of distinct beams of UV light in which each beam inside the periphery of the array overlaps each adjacent beam by at least 70% at the exposure plane. A method for directing light onto an exposure plane in an optical lithography procedure is provided.
David Cohn - Dobbs Ferry NY, US Pankaj Dhoolia - New Delhi, IN Hemesh Kumar - New Delhi, IN Santhosh Kumaran - Peekskill NY, US Rong Liu - Sterling VA, US Florian Pinel - New York NY, US
Assignee:
International Business Machines Corporation - Armonk NY
International Classification:
G06F 9/45
US Classification:
703 22, 718100
Abstract:
Techniques for modeling a composite application are provided. The techniques include identifying one or more entities that are processed in a user enterprise, identifying one or more actions to be performed during a lifecycle of the one or more entities, and modeling a composite application based on the one or more actions to be performed during a lifecycle of the one or more entities.
Methods Of Identifying G-Coupled Receptors Associated With Macrophage-Trophic Hiv, And Diagnostic And Therapeutic Uses Thereof
Dan R. Littman - New York NY Hongkui Deng - Worcester MA Wilfried Ellmeier - New York NY Nathaniel R. Landau - New York NY Rong Liu - New York NY
Assignee:
The Aaron Diamond Aids Research Center - New York NY New York University - New York NY
International Classification:
C12Q 170 G01N 33567 C12N 510
US Classification:
435 5
Abstract:
Entry of HIV-1 into target cells requires cell surface CD4 as well as additional host cell cofactors. A cofactor required for infection with virus adapted for growth in transformed T cell lines was recently identified and named fusin. Fusin, however, does not promote entry of macrophage-tropic viruses that are believed to be the key pathogenic strains in vivo. It has now been determined that the principal cofactor for entry mediated by the envelope glycoproteins of primary macrophage-tropic strains of HIV-1 is CC-CKR5, a receptor for the. beta. -chemokines RANTES, MIP-1. alpha. , and MIP-1. beta.
Nathaniel R. Landau - New York NY Richard A. Koup - Southlake TX Rong Liu - New York NY William Paxton - Amsterdam, NL
Assignee:
The Aaron Diamond Aids Research Center - New York NY
International Classification:
C12Q 168 C12Q 170
US Classification:
435 6
Abstract:
Entry of HIV-1 into target cells requires cell surface CD4 as well as additional host cell cofactors. A cofactor required for infection with virus adapted for growth in transformed T cell lines was recently identified and named fusin. Fusin, however, does not promote entry of macrophage-tropic viruses that are believed to be the key pathogenic strains in vivo. It has now been determined that the principal cofactor for entry mediated by the envelope glycoproteins of primary macrophage-tropic strains of HIV-1 is CC-CKR5, a receptor for the. beta. -chemokines RANTES, MIP-1. alpha. , and MIP-1. beta. It has also been found that individuals who are homozygous for a mutation of the CKR-5 receptor are resistent to HIV infection; in vitro infection requires a 1000-fold higher dose of HIV than normal cells. The mutation results in complete suppression of CKR-5 expression.
G-Coupled Receptors Associated With Macrophage-Trophic Hiv, And Diagnostic And Therapeutic Uses Thereof
Dan R. Littman - New York NY Hongkui Deng - New York NY Wilfried Ellmeier - New York NY Nathaniel R. Landau - New York NY Rong Liu - New York NY
Assignee:
New York University - New York NY The Aaron Diamond Aids Research Center - New York NY
International Classification:
C12N 506 C12N 510 C12N 508
US Classification:
435325
Abstract:
Entry of HIV-1 into target cells requires cell surface CD4 as well as additional host cell cofactors. A cofactor required for infection with virus adapted for growth in transformed T cell lines was recently identified and named fusin. Fusin, however, does not promote entry of macrophage-tropic viruses that are believed to be the key pathogenic strains in vivo. It has now been determined that the principal cofactor for entry mediated by the envelope glycoproteins of primary macrophage-tropic strains of HIV-1 is CC-CKR5, a receptor for the. beta. -chemokines RANTES, MIP-1. alpha. , and MIP-1. beta.
Apr 2011 to 2000 Engineering Program ManagerFoxconn NWE Technology Inc. Santa Clara, CA Aug 2010 to Apr 2011 Mechanical EngineerQuanta Computer Inc. Fremont, CA Feb 2010 to Aug 2010 Project Engineer
Education:
University of California-Los Angeles (UCLA) Los Angeles, CA 2005 to 2009 Bachelor of Science in Mechanical Engineering