Rong Tao Wang

US Patent:

6750061, Jun 15, 2004

Filed:

Apr 5, 2001

Appl. No.:

09/828326

Inventors:

Brian T. Chait - New York NY
Ronald Beavis - Winnipeg, CA
Rong Wang - New York NY
Stephen B. H. Kent - San Francisco CA

Assignee:

The Rockefeller University - New York NY
The Scripps Research Institute - La Jolla CA

International Classification:

G01N 3300

US Classification:

436 89, 436173, 436174, 436178, 250281, 250282

Abstract:

Method is described for sequencing polypeptides by forming peptide ladders comprising a series of polypeptides in which adjacent members of the series vary by one amino acid residue and determining the identity and position of each amino acid in the polypeptide by mass spectroscopy.

US Patent:

7341874, Mar 11, 2008

Filed:

Mar 2, 2004

Appl. No.:

10/792176

Inventors:

Brian T. Chait - New York NY, US
Ronald Beavis - Winnipeg, CA
Rong Wang - New York NY, US
Stephen B. H. Kent - San Francisco CA, US

Assignee:

The Rockefeller University - New York NY
The Scripps Research Institute - La Jolla CA

International Classification:

G01N 33/00

US Classification:

436 89, 436173, 436174, 436178, 530333, 530402, 250281, 250282

Abstract:

This invention provides for novel methods of identifying covalent modifications of an amino acid residue in a polypeptide chain by detecting mass differences.

US Patent:

20050153454, Jul 14, 2005

Filed:

Dec 1, 2004

Appl. No.:

11/001908

Inventors:

Brian Chait - New York NY, US
Ronald Beavis - Winnipeg, CA
Rong Wang - New York NY, US
Stephen Kent - San Francisco CA, US

Assignee:

The Rockefeller University - New York NY
The Scripps Research Institute - La Jolla CA

International Classification:

G01N033/00

US Classification:

436086000

Abstract:

Method is described for sequencing polypeptides by forming peptide ladders comprising a series of polypeptides in which adjacent members of the series vary by one amino acid residue and determining the identity and position of each amino acid in the polypeptide by mass spectroscopy.

US Patent:

45333890, Aug 6, 1985

Filed:

Dec 29, 1980

Appl. No.:

6/220618

Inventors:

Deepak Kapoor - Saddle Brook NJ
Chung-Chu Wan - Rockaway NJ
Rong Y. Wang - Pine Brook NJ

Assignee:

Allied Corporation - Morris Township, Morris County NJ

International Classification:

F16H 2910

US Classification:

75123B

Abstract:

A homogeneous boron containing alloy is disclosed with a composition which can be essentially represented by the formula of: M. sub. i T. sub. j B. sub. k where M is a metal from the group of nickel, iron, cobalt or a mixture thereof; T is a refractory metal from the group of molybdenum, tungsten, or a mixture thereof; and B is the element boron. The subscripts i, j, k are the respective atomic percent of each of the constituents and vary respectively between about 25 and 98, between about 1 and 40, and between 1 and 35 with the proviso that j>k, and i+j+k=100. By further limitation of the chemistry, it is possible to assure the alloy will age harden.

US Patent:

57926646, Aug 11, 1998

Filed:

Jun 7, 1995

Appl. No.:

8/474997

Inventors:

Brian T. Chait - New York NY
Rong Wang - New York NY
Stephen B. H. Kent - La Jolla CA
Steven M. Clark - Palo Alto CA

Assignee:

The Rockefeller University - New York NY
Scripps Research Institute - LaJolla CA
Ciphergen Biosystems, Inc. - Palo Alto CA

International Classification:

G01N 3300
C12P 2106
A61K 3806
G03C 152

US Classification:

436 89

Abstract:

Methods of producing biopolymer ladders and their use to obtain structural information about the biopolymer. The ladders are produced by setting up catalytic cleavage and terminating reactions at the end of biopolymer molecules. The terminating reactions terminate cleavage of a percentage of the biopolymer molecules at each round of cleavage.

US Patent:

62710370, Aug 7, 2001

Filed:

Jun 24, 1996

Appl. No.:

8/341555

Inventors:

Brian T. Chait - New York NY
Ronald Beavis - Winnipeg, CA
Rong Wang - New York NY
Stephen B. H. Kent - San Francisco CA

Assignee:

The Rockefeller University - NY
The Scripps Research Institute - La Jolla

International Classification:

G01N 3300

US Classification:

436 89

Abstract:

Method is described for sequencing polypeptides by forming peptide ladders comprising a series of polypeptides in which adjacent members of the series vary by one amino acid residue and determining the identity and position of each amino acid in the polypeptide by mass spectroscopy.