Thomas Giordano - Ann Arbor MI, US Ronald Koenig - Ann Arbor MI, US Rork Kuick - Dexter MI, US Samir Hanish - Mercer Island WI, US Dafydd G. Thomas - Fenton MI, US Yuri Nikiforov - Pittsburgh PA, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI The University of Cincinnati - Cincinnati OH
International Classification:
C12Q 1/68 G01N 33/53
US Classification:
435 612, 435 6, 435 614, 435 71
Abstract:
The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with thyroid cancers. Genes identified as cancer markers using the methods of the present invention find use in the diagnosis and characterization of thyroid cancer. In addition, the genes provide targets for cancer drug screens and therapeutic applications.
Samir Hanash - Ann Arbor MI, US David Beer - Ann Arbor MI, US Rork Kuick - Ann Arbor MI, US Robert Hinderer - Ann Arbor MI, US
Assignee:
The Regents of the University of Michigan
International Classification:
G01N033/574 C07H021/04 C07K014/475 C07K016/30
US Classification:
435/007230, 530/350000, 530/388800, 536/023500
Abstract:
Computerized analysis of 2-D gels, both carrier ampholyte (CA) and immobilized pH gradient (IPG) based, of the proteins in tissue from esophageal tumors, reveals proteins which are different in tumor and control tissue.
David Beer - Chelsea MI, US Sharon Kardia - Ann Arbor MI, US Thomas Giordano - Ann Arbor MI, US Jeremy Taylor - Ann Arbor MI, US Samir Hanash - Ann Arbor MI, US David Misek - Ann Arbor MI, US Dafydd Thomas - Fenton MI, US Rork Kuick - Dexter MI, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
C12Q001/68 G01N033/574
US Classification:
435/006000, 435/007230
Abstract:
The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with lung cancers. Genes identified as cancer markers find use in the diagnosis and characterization of lung cancer. In addition, the genes provide targets for cancer drug screens and therapeutic applications.
Samir Hanash - Ann Arbor MI, US David Beer - Ann Arbor MI, US Rork Kuick - Ann Arbor MI, US Robert Hinderer - Ann Arbor MI, US
International Classification:
G01N 33/574
US Classification:
435007230
Abstract:
Computerized analysis of 2-D gels, both carrier ampholyte (CA) and immobilized pH gradient (IPG) based, of the proteins in tissue from esophageal tumors, reveals proteins which are different in tumor and control tissue.
Thomas Giordano - Ann Arbor MI, US Ronald Koenig - Ann Arbor MI, US Rork Kuick - Dexter MI, US Samir Hanish - Mercer Island WA, US Yuri Nikiforov - Pittsburgh PA, US Dafydd Thomas - Fenton MI, US
Assignee:
Regents of the University of Michigan - Ann Arbor MI
International Classification:
C12Q 1/68 G01N 33/574
US Classification:
435006000, 435007230
Abstract:
The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with thyroid cancers. Genes identified as cancer markers using the methods of the present invention find use in the diagnosis and characterization of thyroid cancer. In addition, the genes provide targets for cancer drug screens and therapeutic applications.