Raphael Pappo - Skokie IL Rothwell Polk - Northfield IL
Assignee:
G. D. Searle & Co. - Chicago IL
International Classification:
A61K 3171
US Classification:
424181
Abstract:
The administration of aldosterone inhibitors of the spirolactone structural type prior to and during treatment with anti-neoplastic agents such as adriamycin results in retention of the desired activity of the latter substances while inhibiting their undesirable cardiotoxic properties.