Ru W Chen

US Patent:

20080318225, Dec 25, 2008

Filed:

Aug 16, 2007

Appl. No.:

11/840112

Inventors:

Teresa A. Brentnall - Seattle WA, US
Ru Chen - Seattle WA, US
Katherine L. Pogue-Geile - Pittsburgh PA, US
David C. Whitcomb - Allison Park PA, US
Mary Patricia Bronner - Moreland Hills OH, US
Carol A. Otey - Chapel Hill NC, US

International Classification:

C12Q 1/68
G01N 33/53
G01N 33/535

US Classification:

435 6, 435 71, 435 792

Abstract:

The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.

US Patent:

20110104694, May 5, 2011

Filed:

Nov 4, 2010

Appl. No.:

12/939801

Inventors:

Teresa A. Brentnall - Seattle WA, US
Ru Chen - Seattle WA, US
Katherine L. Pogue-Geile - Pittsburgh PA, US
David C. Whitcomb - Allison Park PA, US
Mary Patricia Bronner - Moreland Hills OH, US
Carol A. Otey - Chapel Hill NC, US

Assignee:

University of Washington - Seattle WA
University of North Carolina at Chapel Hill - Chapel Hill NC
University of Pittsburgh - Pittsburgh PA
The Cleveland Clinic Foundation - Cleveland OH

International Classification:

C12Q 1/68

US Classification:

435 6

Abstract:

The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.

US Patent:

20180181259, Jun 28, 2018

Filed:

Dec 27, 2016

Appl. No.:

15/390927

Inventors:

- Redmond WA, US
Patrick J. McVittie - Seattle WA, US
P. Selvan Viswanathan - Bellevue WA, US
Ru Chen - Bellevue WA, US
Justin R. Zilke - Kirkland WA, US

International Classification:

G06F 3/042
G06F 3/041

Abstract:

A projection system emits light pulses in a field of view and measures properties of reflections. Properties may include time of flight and return amplitude. Foreground objects and background surfaces are distinguished, distances between foreground objects and background surfaces are determined based on reflections that are occluded by the foreground objects and other properties of the projection system.