University of Massachusetts, Amherst 1987 - 1990
Post-doc, Polymer Science
Cornell University 1982 - 1987
PhD, Materials Science & Engineering
Gettysburg College 1978 - 1982
BAS, Physics
North Bergen High School 1974 - 1978
Peter I. Lelkes - Cherry Hill NJ, US Mengyan Li - Tampa FL, US Anat Perets - Wynnewood PA, US Pimporn Uttayarat - Philadelphia PA, US Robert J. Levy - Merion Station PA, US Russell J. Composto - Philadelphia PA, US
International Classification:
A61F 2/04 A61F 2/06 B05D 5/00
US Classification:
623 132, 427 224, 623 2371, 606152
Abstract:
The present invention relates to a hybrid graft and methods of generating the hybrid graft. The hybrid graft comprises an exterior surface and a luminal surface. The luminal surface comprises a micropattern of grooves to which cells adhere and orient along. The exterior surface comprises electrospun microfibers wherein the microfibers provide mechanical properties to the graft. The hybrid graft is capable supporting endothelial cell attachment, endothelial cell alignment, cell proliferation, and maintaining their in vivo function. The graft of the invention can recapitulate the in vivo morphology and function of natural vascular endothelium.
Oral Care Compositions And Methods For Anti-Attachment Polymers And Coatings
- New York NY, US - Philadelphia PA, US Lynette ZAIDEL - Cranford NJ, US James MASTERS - Ringoes NJ, US Russell COMPOSTO - Philadelphia PA, US Hyun-Su LEE - Paoli PA, US
Assignee:
Colgate-Palmolive Company - New York NY The Trustees of the University of Pennsylvania - Philadelphia PA
Antimicrobial compositions and methods for depositing or coating the antimicrobial or antibacterial compositions on a substrate to prevent microbial adhesion are provided. The antimicrobial composition may include a cationic polymer having a poly-allylamine backbone. A portion of the poly-allylamine backbone may be functionalized with at least one of a guanidine functional group and a biguanide functional group.
Oral Care Compositions And Methods For Anti-Attachment Polymers And Coatings
- New York NY, US - Philadelphia PA, US Lynette ZAIDEL - Cranford NJ, US James MASTERS - Ringoes NJ, US Russell COMPOSTO - Philadelphia PA, US Hyun-Su LEE - Paoli PA, US
Assignee:
Colgate-Palmolive Company - New York NY The Trustees of the University of Pennsylvania - Philadelphia PA
Antimicrobial compositions and methods for depositing or coating the antimicrobial or antibacterial compositions on a substrate to prevent microbial adhesion are provided. The antimicrobial composition may include a cationic polymer having a poly-allylamine backbone. A portion of the poly-allylamine backbone may be functionalized with at least one of a guanidine functional group and a biguanide functional group.
Small Diameter Vascular Graft Produced By A Hybrid Method
- Philadelphia PA, US Pimporn Uttayarat - Philadelphia PA, US Robert J. Levy - Merion Station PA, US Russell J. Composto - Philadelphia PA, US
International Classification:
A61F 2/00 D01D 5/00 A61F 2/06
Abstract:
The present invention relates to a hybrid graft and methods of generating the hybrid graft. The hybrid graft comprises an exterior surface and a luminal surface. The luminal surface comprises a micropattern of grooves to which cells adhere and orient along. The exterior surface comprises electrospun microfibers wherein the microfibers provide mechanical properties to the graft. The hybrid graft is capable supporting endothelial cell attachment, endothelial cell alignment, cell proliferation, and maintaining their in vivo function. The graft of the invention can recapitulate the in vivo morphology and function of natural vascular endothelium.
- Philadelphia PA, US David M. Eckmann - Wynnewood PA, US Russell Composto - Philadelphia PA, US
International Classification:
A61L 29/08 A61L 29/16
US Classification:
424423, 514 36, 427 224
Abstract:
The invention provides compositions comprising a plurality of polymer layers for preventing or inhibiting microbial infections. Specifically, the invention provides a combination of a cationic polymer layer that resists adhesion of a microbe to its surface and an anionic polymer layer that releases a cationic anti-microbial agent in response to a change in pH or electrostatic balance.
Multifunctional Chitosan Grafted Surfaces And Uses Thereof
Hyun-Su Lee - Wayne PA, US Russell Composto - Philadelphia PA, US David M. Eckmann - Wynnewood PA, US Noreen J. Hickok - Philadelphia PA, US
International Classification:
A61L 29/08 A61L 31/10
US Classification:
536 20
Abstract:
The invention relates to a multifunctional chitosan grafted surface. Specifically, the invention relates to a chitosan modified with a quaternary ammonium salt (CH-Q) grafted surface that provides various functional properties, including stability (pH 3-9) and unique pH dependent swelling and antibacterial properties.
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