Shenda Baker - Upland CA, US William P. Wiesmann - Washington DC, US Ruth Baxter - Los Angeles CA, US Snezna Rogelj - Socorro NM, US
International Classification:
C08B 37/08 C12N 15/85 C12N 15/87
US Classification:
435455, 536 20
Abstract:
The present invention is directed to the delivery of nucleic acids in a non-viral vector to cells by positively charged chitosan derivatives, including but not limited to chitosan-arginine, chitosan-lysine and chitosan-histidine.
Methods And Compositions For Treating Wounds Utilizing Chitosan Compounds
Shenda Baker - Upland CA, US William P. Wiesmann - Washington DC, US Ruth Baxter - Los Angeles CA, US
Assignee:
SYNEDGEN, INC. - Claremont CA
International Classification:
A61K 31/722
US Classification:
514 54
Abstract:
Described herein are methods of treating wounds, the method comprising administering to a subject an effective amount of a composition comprising a soluble or derivatized chitosan wherein the soluble or derivatized chitosan when administered contacts the wound, thereby treating the wound.
- Claremont CA, US Ruth Baxter - Los Angeles CA, US William P. Wiesmann - Chevy Chase MD, US
International Classification:
A61K 47/36 A61K 31/203 A61K 31/4166 A61K 38/18
Abstract:
Described herein are compositions comprising a derivatized polyglucosamine and a small molecule, peptide, or protein and related methods of use, e.g., to deliver a small molecule, peptide, or protein to cells (e.g., cancer cells) or tissues (e.g., mucosal membrane and epithelial membrane), e.g., to treat a disease or condition at a subject.