- Cambridge, GB Nazzareno Dimasi - Gaithersburg MD, US Karen Coffman - Gaithersburg MD, US Ryan Fleming - Gaithersburg MD, US Ping Tsui - Gaithersburg MD, US Changshou Gao - Gaithersburg MD, US Mario A. Cepeda - Winchester MA, US Adrian Schwartz Mittelman - Brookfield CT, US
Assignee:
MEDIMMUNE LIMITED - Cambridge
International Classification:
C07K 16/22 C12N 15/85 A61K 39/00
Abstract:
The present invention relates to bispecific antibodies having activity against a vascular endothelial growth factor (VEGF) and an angiopoietin (ANG), and methods of making and using such bispecific antibodies.
Combination Therapies Using Anti-Pseudomonas Psl And Pcrv Binding Molecules
- CAMBRIDGE, GB Paul WARRENER - Gaithersburg MD, US Charles STOVER - Gaithersburg MD, US Bret SELLMAN - Gaithersburg MD, US Ralph MINTER - Cambridge, GB Sandrine GUILLARD - Cambridge, GB Steven RUST - Cambridge, GB Mladen TOMICH - Exton PA, US Vignesh VENKATRAMAN - Cambridge, GB Reena VARKEY - Gaithersburg MD, US Li PENG - Gaithersburg MD, US Melissa DAMSCHRODER - Gaithersburg MD, US Partha S. CHOWDHURY - Gaithersburg MD, US Nazzareno DIMASI - Gaithersburg MD, US Ryan FLEMING - Gaithersburg MD, US Binyam BEZABEH - Gaithersburg MD, US Changshou GAO - Gaithersburg MD, US Godfrey RAINEY - Gaithersburg MD, US Cuihua GAO - Gaithersburg MD, US
International Classification:
C07K 16/12
Abstract:
This disclosure relates to combination therapies comprising anti-Psl and PcrV binding molecules and related compositions, for use in prevention and treatment of infection.
Anti-Vegf-A And Anti-Ang2 Antibodies And Uses Thereof
- Cambridge, GB Nazzareno Dimasi - Gaithersburg MD, US Karen Coffman - Gaithersburg MD, US Ryan Fleming - Gaithersburg MD, US Ping Tsui - Gaithersburg MD, US Changshou Gao - Gaithersburg MD, US Mario A. Cepeda - Winchester MA, US Adrian Schwartz Mittelman - Brookfield CT, US
International Classification:
C07K 16/22 C12N 15/85
Abstract:
The present invention relates to bispecific antibodies having activity against a vascular endothelial growth factor (VEGF) and an angiopoietin (ANG), and methods of making and using such bispecific antibodies.
- Gaithersburg MD, US Nazzareno Dimasi - Gaithersburg MD, US Steven Coats - Gaithersburg MD, US Melissa Damschroder - Gaithersburg MD, US Changshou Gao - Gaithersburg MD, US Godfrey Rainey - Gaithersburg MD, US Cuihua Gao - Gaithersburg MD, US Dorin Toader - Gaithersburg MD, US Lakshmaiah Gingipalli - Waitham MA, US Fengjiang Wang - Gaithersburg MD, US Ryan Fleming - Gaithersburg MD, US Binyam Bezabeh - Gaithersburg MD, US Andy Qingan Yuan - Monmouth NJ, US Srinath Kasturirangan - Gaithersburg MD, US
International Classification:
C07K 16/32 C07K 16/30
Abstract:
The present invention relates to anti-HER2 binding molecules (e.g., antibodies and antigen binding fragments thereof), derived HER2-binding molecules (e.g., bispecific anti-HER2 antibodies), and antibody-drug conjugates (ADC) that bind the extracellular domain of the HER2 receptor. Also provided are pharmaceutical formulation comprising the disclosed compositions and method for the treating diseases associated with HER2-mediated signal transduction.
Multi-Specific Anti-Pseudomonas Psl And Pcrv Binding Molecules And Uses Thereof
- GAITHERSBURG MD, US - CAMBRIDGE, GB Charles STOVER - Gaithersburg MD, US Bret SELLMAN - Gaithersburg MD, US Ralph MINTER - Cambridge, UK Sandrine GUILLARD - Cambridge, UK Steven RUST - Cambridge, UK Mladen TOMICH - Exton PA, US Vignesh VENKATRAMAN - Cambridge, UK Reena VARKEY - Gaithersburg MD, US Li PENG - Gaithersburg MD, US Melissa DAMSCHRODER - Gaithersburg MD, US Partha CHOWDHURY - Gaithersburg MD, US Nazzareno DIMASI - Gaithersburg MD, US Ryan FLEMING - Gaithersburg MD, US Binyam BEZABEH - Gaithersburg MD, US Changshou GAO - Gaithersburg MD, US Godfrey RAINEY - Gaithersburg MD, US Cuihua GAO - Gaithersburg MD, US
International Classification:
C07K 16/12 A61K 45/06 A61K 39/40
Abstract:
This disclosure relates to combination therapies comprising anti-Psl and PcrV bispecific binding molecules and related compositions, for use in prevention and treatment of infection.
Combination Therapies Using Anti-Pseudomonas Psl And Pcrv Binding Molecules
- Gaithersburg MD, US - Cambridge, GB Charles Stover - Gaithersburg MD, US Bret Sellman - Gaithersburg MD, US Ralph Minter - Cambridge, GB Sandrine Guillard - Cambridge, GB Steven Rust - Cambridge, GB Mladen Tomich - Exton PA, US Vignesh Venkatraman - Cambridge, GB Reena Varkey - Gaithersburg MD, US Li Peng - Gaithersburg MD, US Melissa Damschroder - Gaithersburg MD, US Partha Chowdhury - Gaithersburg MD, US Nazzareno Dimasi - Gaithersburg MD, US Ryan Fleming - Gaithersburg MD, US Binyam Bezabeh - Gaithersburg MD, US Changshou Gao - Gaithersburg MD, US
International Classification:
C07K 16/12 A61K 39/40 A61K 45/06
Abstract:
The disclosure relates to combination therapies comprising anti-Psl and PcrV binding molecules and related compositions, for use in prevention and treatment of infection.
Combination Therapies Using Anti-Pseudomonas Psl And Pcrv Binding Molecules
This disclosure relates to combination therapies comprising anti-Psl and PcrV binding molecules and related compositions, for use in prevention and treatment of infection.