Sally Ann Miller

US Patent:

52197611, Jun 15, 1993

Filed:

Jun 17, 1991

Appl. No.:

7/716430

Inventors:

Richard K. Lankow - Cinnaminson NJ
Sally A. Miller - Pennsauken NJ
G. David Grothaus - Delran NJ
Frank P. Petersen - Beverly NJ
Dennis R. Stocker - Yardley PA
Stephanie L. Papa - Merchantville NJ
James Donovan - Levittown PA
Douglas Malik - Pittsburgh PA

Assignee:

Agri-Diagnostics Associates - Cinnaminson NJ

International Classification:

G01N 102

US Classification:

436177

Abstract:

A method and a kit for testing a plant for a suspected antigen. A sample of the plant is taken and rubbed between first and second pads to extract sap from the sample and to collect the sap on the first pad. The sap is transferred to a liquid solution, and that solution is tested for the suspected antigen. This may be done by contacting the solution with a tag antibody and with a carrier having a capture antibody so that a tag antibody-antigen-capture antibody complex forms on the carrier if the suspected antigen is in the liquid solution. The carrier is then tested for the tag antibody. The kit preferably includes the first and second pads, the carrier, containers to hold the liquid solution and the tag antibody, and a device or reagent to test the carrier for the tag antibody.

US Patent:

48031550, Feb 7, 1989

Filed:

Feb 27, 1986

Appl. No.:

6/834198

Inventors:

Frank P. Petersen - Beverly NJ
Adrianna M. Maybroda - Haddonfield NJ
Sally A. Miller - Pennsauken NJ

Assignee:

Agri-Diagnostics Associates - Cinnaminson NJ

International Classification:

G01N 3353
G01N 33577
C07K 1514

US Classification:

435 7

Abstract:

This invention provides monoclonal antibodies which specifically bind to Sclerotinia homoeocarpa the causative agent of dollarspot disease in plants. Hybridoma producing the antibodies as well as materials and kits for carrying out the detection of Sclerotina homoeocarpa are also disclosed.

US Patent:

52178714, Jun 8, 1993

Filed:

Aug 21, 1990

Appl. No.:

7/570495

Inventors:

Frank P. Petersen - Burlington NJ
Mark D. Clymer - Norristown PA
Sally A. Miller - Pennsauken NJ
James H. Rittenburg - Perkasie PA
G. David Grothaus - Burlington NJ

Assignee:

Ciba-Geigy Corporation - Ardsley NY

International Classification:

G01N 33569
C07K 1528
C12N 500

US Classification:

435 731

Abstract:

The invention relates to monoclonal antibodies that react specifically with members of the genus Leptosphaeria and hybridomas that produce such antibodies. The invention is further directed to a method for making a hybridoma cell line that produces monoclonal antibodies that react specifically with Leptosphaeria nodorum, and a method of obtaining monoclonal antibodies therefrom. Methods and kits for diagnosing Leptosphaeria infections in plant material using such monoclonal antibodies are also within the scope of the invention.

US Patent:

48792179, Nov 7, 1989

Filed:

Apr 28, 1987

Appl. No.:

7/043307

Inventors:

Frank P. Petersen - Beverly NJ
Gary D. Grothaus - Delran NJ
Sally A. Miller - Pennsauken NJ

Assignee:

Agri-Diagnostics Associates - Cinnaminson NJ

International Classification:

G01N 33569
C12Q 104
C12P 2100
C12N 500

US Classification:

435 7

Abstract:

This invention provides monoclonal antibodies useful for the detection of Rhizoctonia infection of plants. Hybridoma producing the antibodies as well as materials and kits for carrying out the detection of the organisms are also disclosed.

US Patent:

48451975, Jul 4, 1989

Filed:

Sep 9, 1985

Appl. No.:

6/773811

Inventors:

Frank P. Petersen - Beverly NJ
Adrianna M. Maybroda - Haddonfield NJ
Gary D. Grothaus - Delran NJ
Sally A. Miller - Pennsauken NJ

Assignee:

Agri-Diagnostics Associates - Cinnaminson NJ

International Classification:

C12N 500
C07K 1504
A61K 39395

US Classification:

530387

Abstract:

This invention provides monoclonal antibodies useful for the detection of Phythiaceae infection of plants. Hybridoma producing the antibodies as well as materials and kits for carrying out the detection of the organisms are also disclosed.

US Patent:

51870649, Feb 16, 1993

Filed:

Dec 20, 1988

Appl. No.:

7/287365

Inventors:

Frank P. Petersen - Burlington NJ
Adrianna Maybroda - Trenton NJ
Sally A. Miller - Pennsauken NJ

Assignee:

Agri-Diagnostics Associates - Cinnaminson NJ

International Classification:

C07K 1502
C12Q 104
G01N 33577

US Classification:

435 731

Abstract:

This invention provides monoclonal antibodies useful for the detection of Sclerotinia infection of plants. Hybridoma producing the antibodies as well as materials and kits for carrying out the detection of the organisms are also disclosed.

US Patent:

50472070, Sep 10, 1991

Filed:

May 20, 1986

Appl. No.:

6/865379

Inventors:

Richard K. Lankow - Cinnaminson NJ
Sally A. Miller - Pennsauken NJ
G. David Grothaus - Delran NJ
Frank P. Petersen - Beverly NJ
Dennis R. Stocker - Yardley PA
Stephanie L. Papa - Merchantville NJ
James Donovan - Levittown PA
Douglas Malik - Pittsburgh PA

Assignee:

Agri-Diagnostics Associates - Cinnaminson NJ

International Classification:

G01N 102

US Classification:

422 58

Abstract:

A method and a kit for testing a plant for a suspected antigen. A sample of the plant is taken and rubbed between first and second pads to extract sap from the sample and to collect the sap on the first pad. The sap is transferred to a liquid solution, and that solution is tested for the suspected antigen. This may be done by contacting the solution with a tag antibody and with a carrier having a capture antibody so that a tag antibody-antigen-capture antibody complex forms on the carrier if the suspected antigen is in the liquid solution. The carrier is then tested for the tag antibody. The kit preferably includes the first and second pads, the carrier, containers to hold the liquid solution and the tag antibody, and a device or reagent to test the carrier for the tag antibody.

US Patent:

55589979, Sep 24, 1996

Filed:

Sep 26, 1994

Appl. No.:

8/311813

Inventors:

Frank P. Petersen - Burlington NJ
Mark D. Clymer - Norristown PA
Sally A. Miller - Pennsauken NJ
James H. Rittenburg - Perkasie PA
G. David Grothaus - Burlington NJ

Assignee:

Ciba-Geigy Corporation - Tarrytown NY

International Classification:

G01N 3353
G01N 33569
C07K 1600
C12P 2108

US Classification:

435 731

Abstract:

The invention relates to monoclonal antibodies that react specifically with members of the genus Mycosphaerella and hybridomas that produce such antibodies. The invention is further directed to a method for making a hybridoma cell line that produces monoclonal antibodies that react specifically with at least one species of Mycosphaerella, and a method of obtaining monoclonal antibodies therefrom. Methods and kits for diagnosing Mycosphaerella infections in plant material using such monoclonal antibodies are also within the scope of the invention.