Salvatore Salomone
age ~80
from Florham Park, NJ
Salvatore Salomone Phones & Addresses
- Florham Park, NJ
- Avenel, NJ
- New York, NY
- Waltham, MA
- Whippany, NJ
Us Patents
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Methods And Compositions For The Regulation Of Vasoconstriction
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US Patent:20010041688, Nov 15, 2001
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Filed:Mar 13, 2001
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Appl. No.:09/804987
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Inventors:Christian Waeber - Boston MA, US
Michael Moskowitz - Belmont MA, US
Shin-Ichi Yoshimura - Zurich, CH
Salvatore Salomone - Somerville MA, US -
International Classification:A61K038/19
A61K031/685 -
US Classification:514/078000, 424/085100
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Abstract:Methods and compositions for the treatment of conditions which would benefit from vasoconstriction or the inhibition of vasoconstriction via modulation of sphingosine kinase and sphingosine-1-phosphate phosphatase activity and EDG receptor signaling are provided. These conditions include migraine, stroke, subarachnoid hemorrhage and vasospasm. Also provided are screening methods for modulators of sphingosine kinase and sphingosine-1-phosphate phosphatase activity and EDG receptor signaling which are capable of regulating vasoconstriction.
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