Samuel Scott Beckey

US Patent:

6468800, Oct 22, 2002

Filed:

Apr 21, 1999

Appl. No.:

09/296436

Inventors:

Chari Stylli - San Diego CA
Samuel S. Beckey - San Diego CA
Christopher Bentley Shumate - La Jolla CA
Peter J. Coassin - Encinitas CA

Assignee:

Vertex Pharmaceuticals (San Diego), LLC - San Diego CA

International Classification:

G01N 3502

US Classification:

436 43, 436 47, 436 48, 436164, 436180, 422 63, 422 65, 422 67, 422 8205, 422100, 702 22

Abstract:

The present invention provides for systems and methods that utilize automated and integratable workstations for identifying chemicals having useful activity. The present invention is also directed to chemical entities and information (e. g. , chemical or biological activities of chemicals) generated or discovered by operation of workstations of the present invention. The present invention includes automated workstations that are programmably controlled to minimize processing times at each workstation and that can be integrated to minimize the processing time of the liquid samples from the start to finish of the process.

US Patent:

6472218, Oct 29, 2002

Filed:

Apr 21, 1999

Appl. No.:

09/296435

Inventors:

Chari Stylli - San Diego CA
Samuel S. Beckey - San Diego CA
Christopher Bentley Shumate - La Jolla CA
Peter J. Coassin - Encinitas CA

Assignee:

Vertex Pharmaceuticals (San Diego), LLC - San Diego CA

International Classification:

G01N 3502

US Classification:

436 48, 436 43, 436 47, 436164, 422 63, 422 65, 422 67, 422100, 414277, 414281, 1983461

Abstract:

Substances having useful pharmacological properties are identified by candidate screeners and screening methods. The substances may be incorporated into medicaments. The substances may have modulating activity with respect to pre-defined molecular targets.

US Patent:

6678577, Jan 13, 2004

Filed:

Apr 21, 1999

Appl. No.:

09/296434

Inventors:

Chari Stylli - San Diego CA
Samuel S. Beckey - San Diego CA
Christopher Bentley Shumate - La Jolla CA
Peter J. Coassin - Encinitas CA

Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA

International Classification:

G06F 700

US Classification:

700218, 700213, 422 65, 422 67, 436 47, 436 48

Abstract:

The present invention provides for systems and methods that utilize automated and integratable workstations for identifying chemicals having useful activity. The present invention is also directed to chemical entities and information (e. g. , chemical or biological activities of chemicals) generated or discovered by operation of workstations of the present invention. The present invention includes automated workstations that are programmably controlled to minimize processing times at each workstation and that can be integrated to minimize the processing time of the liquid samples from the start to finish of the process.

US Patent:

6685884, Feb 3, 2004

Filed:

Apr 7, 1999

Appl. No.:

09/287957

Inventors:

Chari Stylli - San Diego CA
Samuel S. Beckey - San Diego CA
Christopher Bentley Shumate - La Jolla CA
Peter J. Coassin - Encinitas CA

Assignee:

Vertex Pharmaceuticals, Inc. - San Diego CA

International Classification:

G01N 3502

US Classification:

422 63, 422 65, 422104, 414277, 1983472, 198348

Abstract:

A high throughput chemical screening method uses methods of concurrent transport and/or processing to increase throughput. A screener may concurrently retrieve chemicals from an addressable chemical storage module and deliver chemicals to a liquid handling module. The screener may also use one transport lane for moving chemicals away from a storage module, and a second transport lane for moving chemicals toward the storage module.

US Patent:

6890485, May 10, 2005

Filed:

Feb 19, 1999

Appl. No.:

09/252842

Inventors:

Chari Stylli - San Diego CA, US
Samuel S. Beckey - San Diego CA, US
Christopher Bentley Shumate - LaJolla CA, US
Peter J. Coassin - Encinitas CA, US

Assignee:

Aurora Discovery, Inc. - San Diego CA

International Classification:

G01N015/06
G01N021/00
G01N033/00
G01N033/48
G01N035/00

US Classification:

422 681, 422 50, 422 55, 422 62, 422 63, 422 64, 422 65, 422 66, 422 67, 422 81, 436 43, 436 44, 436 47, 436 48, 436 49, 436 63, 436174, 436180

Abstract:

A high throughput chemical handling system includes a chemical storage module, a transport module, and one or more liquid handling modules. The transport module may implement parallel chemical transport, and the system may include a plurality of asynchronously operable liquid handling modules coupled to the parallel transport module.

US Patent:

20050191670, Sep 1, 2005

Filed:

Jan 24, 2005

Appl. No.:

11/042810

Inventors:

Chari Stylli - San Diego CA, US
Samuel Beckey - San Diego CA, US
Christopher Shumate - La Jolla CA, US
Peter Coassin - Encinitas CA, US

International Classification:

C12Q001/68
G01N033/53
G06F019/00
G01N033/48
G01N033/50

US Classification:

435006000, 435007100, 702019000

Abstract:

A high throughput chemical handling system includes a chemical storage module, a transport module, and one or more liquid handling modules. The transport module may implement parallel chemical transport, and the system may include a plurality of asynchronously operable liquid handling modules coupled to the parallel transport module.

US Patent:

20060129568, Jun 15, 2006

Filed:

Dec 13, 2004

Appl. No.:

10/905049

Inventors:

Samuel Beckey - Rancho Santa Fe CA, US

International Classification:

G06F 7/00

US Classification:

707100000

Abstract:

A system and method for organizing information pertaining to creative and ad-hoc processes, such as are used in research. Information is stored in a database and indexed simultaneously in three dimensions, representing protocol, objects, and activity. Indexes within each dimension reflect best industry practice and can include object, clustered, indexed, and hierarchical views, while the invention is distinguished by maintaining three indexes simultaneously.

US Patent:

20080226498, Sep 18, 2008

Filed:

Jan 9, 2008

Appl. No.:

11/971826

Inventors:

Chari Stylli - San Diego CA, US
Samuel S. Beckey - San Diego CA, US
Christopher Bentley Shumate - La Jolla CA, US
Peter J. Coassin - Encinitas CA, US

International Classification:

G01N 35/02
G01N 35/10

US Classification:

422 63

Abstract:

A high throughput chemical handling system includes a chemical storage module, a transport module, and one or more liquid handling modules. The transport module may implement parallel chemical transport, and the system may include a plurality of asynchronously operable liquid handling modules coupled to the parallel transport module.