Samuel I Trotz

US Patent:

44827156, Nov 13, 1984

Filed:

Feb 26, 1982

Appl. No.:

6/352813

Inventors:

Samuel I. Trotz - Orange CT
Douglas A. Farmer - Madison CT

Assignee:

Olin Corporation - Cheshire CT

International Classification:

C07D21389

US Classification:

546 6

Abstract:

Disclosed is a process for producing a zinc pyrithione product having an acceptable white or off-white color and preventing or reducing discoloration of sodium pyrithione solutions by treating said sodium pyrithione solutions (which are precursors to zinc pyrithione) with an effective amount of a selected reducing agent to prevent or reduce the discoloration, said reducing agent selected from the class consisting of alkali metal sulfites, alkali metal bisulfites, hydrazine, and mixtures thereof.

US Patent:

55893422, Dec 31, 1996

Filed:

Nov 19, 1990

Appl. No.:

7/615095

Inventors:

Jon R. Geiger - West Hartford CT
Samuel I. Trotz - Orange CT

Assignee:

Olin Corporation - Cheshire CT

International Classification:

C12Q 168

US Classification:

435 6

Abstract:

A method and a kit for separating double-stranded nucleic acid molecules from a mixture containing both single-stranded and double-stranded nucleic acid molecules. The method is particularly suitable for separating hybridized from unhybridized probe nucleic acid.

US Patent:

50343149, Jul 23, 1991

Filed:

Dec 22, 1986

Appl. No.:

6/944919

Inventors:

Jon R. Geiger - West Hartford CT
Samuel I. Trotz - Orange CT

Assignee:

Olin Corporation - Cheshire CT

International Classification:

C12Q 168

US Classification:

435 6

Abstract:

A method and a kit for separating double-stranded nucleic acid molecules from a mixture containing both single-stranded and double-stranded nucleic acid molecules. The method is particularly suitable for separating hybridized from unhybridized probe nucleic acid.

US Patent:

45658560, Jan 21, 1986

Filed:

Oct 12, 1984

Appl. No.:

6/660208

Inventors:

Samuel I. Trotz - Orange CT
Theodore H. Fedynyshyn - Branford CT

Assignee:

Olin Corporation - Cheshire CT

International Classification:

C08F 2606

US Classification:

526265

Abstract:

Disclosed is a bioactive polymer comprising an effective biocidal amount of moieties derived from pyrithione and having the formula ##STR1## wherein R. sub. 1, R. sub. 2 and R. sub. 3 are individually selected from hydrogen and alkyl groups having from 1 to 4 carbon atoms; and PT represents the pyrithione moiety which is defined as ##STR2## wherein R. sub. 4, R. sub. 5, R. sub. 6 and R. sub. 7 are individually selected from hydrogen and, a lower alkyl group having from 1 to about 8 carbon atoms, a lower alkoxy group having from 1 to about 8 carbon atoms, a nitro group and a halo group.

US Patent:

46328815, Dec 30, 1986

Filed:

Feb 26, 1986

Appl. No.:

6/832960

Inventors:

Samuel I. Trotz - Orange CT
Theodore H. Fedynyshyn - Branford CT

Assignee:

Olin Corporation - Cheshire CT

International Classification:

B27K 340

US Classification:

428541

Abstract:

Disclosed is a bioactive polymer comprising an effective biocidal amount of moieties derived from pyrithione and having the formula ##STR1## wherein R. sub. 1, R. sub. 2 and R. sub. 3 are individually selected from hydrogen and alkyl groups having from 1 to 4 carbon atoms; and PT represents the pyrithione moiety which is defined as ##STR2## wherein R. sub. 4, R. sub. 5, R. sub. 6 and R. sub. 7 are individually selected from hydrogen and, a lower alkyl group having from 1 to about 8 carbon atoms, a lower alkoxy group having from 1 to about 8 carbon atoms, a nitro group and a halo group.

US Patent:

45337365, Aug 6, 1985

Filed:

Jul 2, 1984

Appl. No.:

6/626951

Inventors:

Samuel I. Trotz - Orange CT
Douglas A. Farmer - Madison CT

Assignee:

Olin Corporation - Cheshire CT

International Classification:

A61K 3144
C07D21389

US Classification:

546290

Abstract:

Disclosed is a process for producing a zinc pyrithione product having an acceptable white or off-white color and preventing or reducing discoloration of sodium pyrithione solutions by treating said sodium pyrithione solutions (which are precursors to zinc pyrithione) with an effective amount of a selected reducing agent to prevent or reduce the discoloration, said reducing agent selected from the class consisting of alkali metal sulfites, alkali metal bisulfites, hydrazine, and mixtures thereof.

US Patent:

45968640, Jun 24, 1986

Filed:

Oct 7, 1985

Appl. No.:

6/784930

Inventors:

Samuel I. Trotz - Orange CT
Theodore H. Fedynyshyn - Branford CT

Assignee:

Olin Corporation - Cheshire CT

International Classification:

C08F 2606
C08K 534
C08K 516
A61K 3174

US Classification:

526265

Abstract:

Disclosed is a bioactive polymer comprising an effective biocidal amount of moieties derived from pyrithione and having the formula ##STR1## wherein R. sub. 1, R. sub. 2 and R. sub. 3 are individually selected from hydrogen and alkyl groups having from 1 to 4 carbon atoms; and PT represents the pyrithione moiety which is defined as ##STR2## wherein R. sub. 4, R. sub. 5, R. sub. 6 and R. sub. 7 are individually selected from hydrogen and, a lower alkyl group having from 1 to about 8 carbon atoms, a lower alkoxy group having from 1 to about 8 carbon atoms, a nitro group and a halo group.