Sandra J Fenton

US Patent:

20150087812, Mar 26, 2015

Filed:

Mar 11, 2013

Appl. No.:

14/381227

Inventors:

Ellen Chi - San Diego CA, US
Thai Dinh - San Diego CA, US
Suzanne Edavettal - San Diego CA, US
Sandra Fenton - San Diego CA, US
Damon Hamel - San Diego CA, US
Sheri Moores - Spring House PA, US
Jose Pardinas - Spring House PA, US
H. Mimi Zhou - San Diego CA, US
Barry L. Ziober - Spring House PA, US

Assignee:

JANSSEN BIOTECH, INC. - Horsham PA

International Classification:

C07K 16/40

US Classification:

5303879, 53038826

Abstract:

Antibodies and compositions capable of binding and, in a particular aspect, inhibiting the lysophosphatidylipase D activity of human autotaxin protein. The antibodies or are useful in detecting human autotaxin protein and treating diseases and disorders associated with unwanted lysophosphatidylipase D and the presence of lysophosphatidic acid, such as cancer and pulmonary diseases.