Sang H Kim

US Patent:

20120192299, Jul 26, 2012

Filed:

Jan 21, 2011

Appl. No.:

13/011799

Inventors:

Sang Yong Kim - Greenlawn NY, US

Assignee:

Cold Spring Harbor Laboratory - Cold Spring Harbor NY

International Classification:

A01K 67/027
C12N 5/10
C12N 5/07

US Classification:

800 18, 435354

Abstract:

Described herein are inbred B6 ES cell lines that exhibit high developmental capacities and have a number of advantages over ES cell lines already available. First, they can be used for gene targeting and have a high percentage of germline transmission when injected into diploid host blastocysts (50-80%). Second, these ES cell lines can successfully be used to generate live pups by tetraploid blastocyst complementation, producing a high percentage (15-20%) of mice that are entirely inbred B6 ES cell derived. Third, these ES cells lines can be used to rapidly generate mice that are homozygous for a gene of interest. These advantages indicate that the inbred B6 ES cells provided here facilitate the rapid generation of inbred B6 mouse models in a cost-effective and efficient manner.

US Patent:

60746742, Jun 13, 2000

Filed:

Jul 20, 1998

Appl. No.:

9/119099

Inventors:

Michael Joseph Jay - Lexington KY
G. Thomas Kluemper - Lexington KY
Sang Hun Kim - Lexington KY

Assignee:

University of Kentucky Research Foundation - Lexington KY

International Classification:

A61K 950

US Classification:

424502

Abstract:

The present invention provides, inter alia, formulations useful to ameliorate symptoms associated with mucosal abrasions, specifically those due to dental orthodontic brackets; oral surgery; periodontal surgery or other procedures. For instance, there is a formulation comprising: 65 to 75% microcrystalline wax; 5 to 15% non-ionic polymer; 15 to 25% topical anesthetic; and 1 to 5% surfactant, wherein the ratio of non-ionic polymer to microcrystalline wax is no greater than 0. 2. Preferably, for solid topical anesthetics, the particle size is less than the apertures of a 100-mesh screen. However, the topical anesthetic may also be a liquid. Formulations wherein the mixture is a homogeneous matrix is preferred.

Address:

309 Beckley Wood Dr, Louisville, KY 40245

Phone:

(502)2457307

VIN:

4T1BE46K47U110042

Make:

TOYOTA

Model:

CAMRY

Year:

2007