Joseph Guiles - Lafayette CO, US Xicheng Sun - Superior CO, US Nebojsa Janjic - Boulder CO, US Sarah Strong - Louisville CO, US Albert Charles Gyorkos - Westminster CO, US
Novel compounds in enantiomeric excess that are inhibitors of bacterial methionyl synthetase (MetRS) are disclosed. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, and in particular their use in therapy for infection.
Antibacterial Amide And Sulfonamide Substituted Heterocyclic Urea Compounds
Joseph Guiles - Lafayette CO, US Thale Jarvis - Boulder CO, US Sarah Strong - Louisville CO, US Xicheng Sun - Broomfield CO, US Jian Qiu - Longmont CO, US John C. Rohloff - Boulder CO, US
The present invention provides novel amide and sulfonamide substituted heterocyclic urea compounds having useful antibacterial activity. Use of these compounds as pharmaceutical compositions and method of their production are also provided.
Antibacterial Sulfone And Sulfoxide Substituted Heterocyclic Urea Compounds
Joseph Guiles - Lafayette CO, US Thale Jarvis - Boulder CO, US Sarah Strong - Louisville CO, US Xicheng Sun - Broomfield CO, US Jian Qiu - Longmont CO, US John C. Rohloff - Boulder CO, US
The present invention provides novel sulfone and sulfoxide substituted heterocyclic urea compounds having useful antibacterial activity. Use of these compounds as pharmaceutical compositions and methods of production are provided.
Substituted Thienopyridone Compounds With Antibacterial Activity
Novel bicyclic heteroaromatic compounds are provided that are inhibitors of bacterial methionyl tRNA synthetase (MetRS). Compounds of the invention generally have a left hand side chroman group or left hand side tetrahydroquinoline group and a right hand side thienopyridone group. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, particularly as anti-agents.
Joseph Guiles - Lafayette CO, US Thale Jarvis - Boulder CO, US Sarah Strong - Louisville CO, US Xicheng Sun - Superior CO, US
Assignee:
Replidyne, Inc. - Louisville CO
International Classification:
A61K 31/433 A61K 31/426 C07D 285/08
US Classification:
514362, 514371, 548194, 548128
Abstract:
The present invention provides novel heterocyclic urea compounds having useful antibacterial activity, pharmaceutical compositions comprising one or more of these compounds, methods of making the same, and methods of using the same.
Substituted Phenylether-Thienopyridone Compounds With Antibacterial Activity
JOSEPH GUILES - LAFAYETTE CO, US XICHENG SUN - SUPERIOR CO, US NEBOJSA JANJIC - BOULDER CO, US SARAH STRONG - LOUISVILLE CO, US
Assignee:
REPLIDYNE, INC. - Louisville CO
International Classification:
A61K 31/4365 C07D 221/04 A61P 31/04
US Classification:
514301, 546114
Abstract:
Novel bicyclic heteroaromatic compounds are provided that are inhibitors of bacterial methionyl tRNA synthetase (MetRS). Compounds of the invention generally have a left hand side phenylether constituent and a right hand side thienopyridone constituent. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, particularly as anti-agents.
Methods And Compounds For Treatment Of Clostridium Based Infection
Gary J. Rosenthal - Lafayette CO, US Xicheng Sun - Broomfield CO, US Sarah Strong - Louisville CO, US Jian Qiu - Longmont CO, US
Assignee:
N30 Pharmaceuticals, Inc. - Boulder CO
International Classification:
C07D 403/06 C07D 409/14
US Classification:
514382, 514381
Abstract:
The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
Ibm Oct 1, 2013 - Jul 2020
Recruitment Specialist - Talent Acquisition Optimization
Ibm Supporting Flowserve Corporation Oct 1, 2013 - Jul 2020
Lead Recruiter
Dpc&S Incorporated Feb 2011 - Oct 2013
Human Resources and Office Manager
Preudhomme Law Group Feb 2011 - Oct 2013
Legal Assistant
Matrix Absence Management Apr 2006 - Feb 2010
Project Manager
Education:
Maricopa Community Colleges
Skills:
Human Resources Recruiting Customer Service Employee Benefits Management Onboarding Interviews Training Microsoft Office Employee Relations Performance Management Talent Acquisition Process Improvement Administration Benefits Administration Team Building Applicant Tracking Systems Hiring Microsoft Excel Outlook Sourcing
Interests:
Social Services Children Education Human Rights Health
Certifications:
Ibm Design Thinking Practitioner Ibm Agile Explorer Enterprise Design Thinking Co-Creator Data Science Foundations - Level 1
Dr. Strong graduated from the Michigan State University College of Osteopathic Medicine in 2002. She works in Holland, MI and 1 other location and specializes in Obstetrics & Gynecology. Dr. Strong is affiliated with Butterworth Hospital, Holland Hospital, Spectrum Health Reed City Hospital and Spectrum Health Zeeland Community Hospital.
Youtube
Sarah Strong Symbols of Peace
Sarah Strong, current student of the Herron School of Art, describes h...
Category:
Education
Uploaded:
25 Apr, 2008
Duration:
3m 46s
Sarah Strong + Justin Jaffray Team BLD -- 1:0...
After C3 at a restaurant in Kitchener.
Category:
People & Blogs
Uploaded:
29 Jul, 2009
Duration:
1m 25s
Official 3x3x3 average of 5: 14.89 seconds
my official PB 3x3x3 average, it took me over eight months (7 competit...
Category:
Pets & Animals
Uploaded:
07 Dec, 2009
Duration:
1m 44s
TOW2009 -- Andrej Vs. Sarah (UNOFFICIAL)
Random unofficial solves I taped of Sarah Strong (Sa967st) vs. Andrej ...
Category:
Sports
Uploaded:
09 Mar, 2009
Duration:
2m 52s
TEDxAdelaide - Sarah Strong-Law - Building Co...
Hear from Sarah Strong-Law. Sarah is a very happy immigrant from Austi...
Category:
Nonprofits & Activism
Uploaded:
17 Dec, 2010
Duration:
14m 54s
Sarah Strong - Scene from Closer
Audition-style performance of a scene from Closer. Contact Sarah Stron...
Category:
Film & Animation
Uploaded:
14 Mar, 2008
Duration:
5m 27s
Googleplus
Sarah Strong
Education:
University of Waterloo - Combinatorics and Optimization, Classical Studies
ys spent by hospital beds as much as nights spent on the courtUConn did not waste any time. The best team in the country was led by its best players to play its best basketball. Dynamic forward Sarah Strong broke a freshman championship scoring record. Azzi Fudd opened with a dominant first half. Pai
UConn whipped the ball all over the floor in the title clash, finishing with 18 assists on 30 field goals. Bueckers totaled just 17 points, while Azzi Fuddwho took home the Final Four Most Outstanding Player awardand freshman sensation Sarah Strong poured in 24 each.
Date: Apr 07, 2025
Category: Sports
Source: Google
NCAA championship: Paige Bueckers' culminating title moment took something extra — and her UConn teammates delivered
supporting cast shed never been able to lean on in years prior as injuries ravaged the roster and Auriemma piecemealed plans. The celebrations and cheers, the trophy, the honors were won not by a singular Bueckers effort, but a combination of three-headed attack that included Fudd and Sarah Strong.
Date: Apr 06, 2025
Category: Sports
Source: Google
Women's March Madness scores, Elite Eight updates: Final Four set as UConn handles USC, Texas tops TCU
Bueckers finished with 31 points, three rebounds, six assists, four steals and two blocks for her third consecutive 30-point game, while Sarah Strong went for 22 points, 17 rebounds and four assists to become the first UConn freshman with a 20/10 game in the Elite Eight or later.
Freshman Sarah Strong became the first freshman in UConn history with a 20-point, 10-rebound game in the Elite Eight or later. She kept the Huskies afloat early with 10 of their 14 first-quarter points, helping them take the lead after trailing 11-5 early and jump ahead by as many as nine.
Date: Mar 31, 2025
Category: Sports
Source: Google
Women's March Madness scores, Sweet 16 live updates: UConn, Texas seek to reach Elite Eight; Notre Dame falls
Paige Bueckers and UConn are facing Raegan Beers and Oklahoma. The Huskies have the advantage in the backcourt with Bueckers and Fudd finally healthy and dominant together, while Beers' presence down low will be a challenge for star freshman Sarah Strong. Whoever wins this game will meet USC or Kans
San Mateo Christian Academy San Mateo CA 1986-1988, San Ramon Valley Christian Academy Danville CA 1992-1995, Contra Costa Christian School Walnut Creek CA 1995-1999
Community:
Mark Christianson, Barbara Van Duyn, Judy Mcadoo, Alice Sontheimer