Scott Gordon Corey

US Patent:

20180161769, Jun 14, 2018

Filed:

Jan 24, 2018

Appl. No.:

15/879329

Inventors:

- CARLSBAD CA, US
SEAN FORD - CARLSBAD CA, US
VAMSEE K. PAMULA - CARY NC, US
VIJAY SRINIVASAN - CARY NC, US
SCOTT COREY - HYDES MD, US
BRIAN MURPHY - CARLSBAD CA, US
DAVID WALTER WRIGHT - LITTLETON CO, US
DOMINIC AIELLO - DENVER CO, US

Assignee:

GENMARK DIAGNOSTICS, INC. - CARLSBAD CA

International Classification:

B01L 3/00
B01L 7/00

Abstract:

In one embodiment, a multiplex fluid processing cartridge includes a sample well, a deformable fluid chamber, a mixing well with a mixer disposed therein, a lysis chamber including a lysis mixer, an electrowetting grid for microdroplet manipulation, and electrosensor arrays configured to detect analytes of interest. An instrument for processing the cartridge is configured to receive the cartridge and to selectively apply thermal energy, magnetic force, and electrical connections to one or more discrete locations on the cartridge and is further configured to compress the deformable chamber(s) in a specified sequence.