Scott A Robertson

US Patent:

20170259083, Sep 14, 2017

Filed:

Mar 14, 2016

Appl. No.:

15/069688

Inventors:

- Minato-ku, JP
- Otawara-shi, JP
- Baltimore MD, US
Rachel-Louise Kvertus KOKTAVA - Edinburgh, GB
Kosuke SAKAUE - Otawara-shi, JP
Todd MCNUTT - Baltimore MD, US
Harry QUON - Baltimore MD, US
Scott Patrick ROBERTSON - Baltimore MD, US
Zhi CHENG - Baltimore MD, US

Assignee:

KABUSHIKI KAISHA TOSHIBA - Minato-ku
TOSHIBA MEDICAL SYSTEMS CORPORATION - Otawara-shi
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD

International Classification:

A61N 5/10
A61B 6/03
A61B 6/06
A61B 6/00
G06T 7/00
G06T 11/00

Abstract:

An apparatus for determining a contour of a treatment region in a patient includes a computer processor to receive input regarding a contour of at least one organ-at-risk (OAR) adjacent to the treatment region; receive input regarding an initial contour of the treatment region; predict a radiation toxicity to the at least one OAR based on the contour of the at least one OAR, the initial contour of the treatment region, and a radiation treatment regimen; determine whether the predicted radiation toxicity exceeds a threshold; and determine a contour of the treatment region by iteratively modifying the initial contour of the treatment region, and any subsequent modified contours of the treatment region, until a stopping condition is satisfied. The stopping condition can be a preselected number of iterations or that the predicted radiation toxicity using the contour in place of the initial contour is first calculated is below said threshold.