Scott F Shaffer

US Patent:

7064125, Jun 20, 2006

Filed:

Nov 13, 2003

Appl. No.:

10/712900

Inventors:

Baoqing Gong - Shoreline WA, US
John Tulinsky - Seattle WA, US
Lynn Bonham - Seattle WA, US
J. Peter Klein - Vashon WA, US
Robert E. Finney - Shoreline WA, US
David M. Hollenback - Seattle WA, US
Scott A. Shaffer - Seattle WA, US
Norina M. Tang - Ann Arbor MI, US
Thayer H. White - Bellevue WA, US
David W. Leung - Mercer Island WA, US

Assignee:

Cell Therapeutics, Inc. - Seattle WA

International Classification:

A01N 43/66

US Classification:

514241, 544196, 544198, 544204, 544207, 544215

Abstract:

The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

US Patent:

7199238, Apr 3, 2007

Filed:

Sep 12, 2005

Appl. No.:

11/224340

Inventors:

Lynn Bonham - Seattle WA, US
Baoqing Gong - Shoreline WA, US
Robert E Finney - Shoreline WA, US
David M Hollenback - Seattle WA, US
J. Peter Klein - Vashon WA, US
David W Leung - Mercer Island WA, US
Scott A Shaffer - Seattle WA, US
Norina M Tang - Ann Arbor MI, US
John Tulinsky - Seattle WA, US
Thayer H White - Bellevue WA, US

Assignee:

Cell Therapuetics, Inc. - Seattle WA

International Classification:

C07D 251/52
C07D 251/38
A61K 31/53
A61P 35/00

US Classification:

544206, 544208, 544213, 514241

Abstract:

The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

US Patent:

7608620, Oct 27, 2009

Filed:

Nov 16, 2006

Appl. No.:

11/601513

Inventors:

Lynn Bonham - Seattle WA, US
Baoqing Gong - Shoreline WA, US
Robert E Finney - Shoreline WA, US
David M Hollenback - Seattle WA, US
J Peter Klein - Vashon WA, US
David W Leung - Mercer Island WA, US
Scott A Shaffer - Seattle WA, US
Norina M Tang - Ann Arbor MI, US
John Tulinsky - Seattle WA, US
Thayer H White - Bellevue WA, US

Assignee:

Cell Therapeutics, Inc. - Seattle WA

International Classification:

C07D 251/52
C07D 251/38
A61K 31/53
A61P 35/00

US Classification:

514245, 544197, 544198, 544205, 544206, 544207, 544208, 544209, 544210

Abstract:

The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

US Patent:

20020103195, Aug 1, 2002

Filed:

Oct 31, 2001

Appl. No.:

09/984888

Inventors:

Lynn Bonham - Seattle WA, US
J. Klein - Vashon WA, US
Robert Finney - Shoreline WA, US
David Hollenback - Seattle WA, US
Scott Shaffer - Seattle WA, US
Norina Tang - Ann Arbor MI, US
Thayer White - Bellevue WA, US
David Leung - Mercer Island WA, US

Assignee:

CELL THERAPEUTICS,INC.

International Classification:

A61K031/5377
A61K031/53
C07D413/14
C 07D 4 3/14

US Classification:

514/236200, 514/245000, 514/232200, 544/083000, 544/113000, 544/209000

Abstract:

The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase (LPAAT-) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT- activity.

US Patent:

20020107269, Aug 8, 2002

Filed:

Oct 31, 2001

Appl. No.:

09/984889

Inventors:

Lynn Bonham - Seattle WA, US
J. Klein - Vashon WA, US
Robert Finney - Shoreline WA, US
David Hollenback - Seattle WA, US
Scott Shaffer - Seattle WA, US
Norina Tang - Ann Arbor WA, US
Thayer White - Bellevue WA, US
David Leung - Mercer Island WA, US

Assignee:

CELL THERAPEUTICS, INC.

International Classification:

A61K031/428
A61K031/423
A61K031/4184
C07D277/60
C07D263/56

US Classification:

514/367000, 514/375000, 514/394000, 548/310100, 548/224000, 548/152000

Abstract:

The invention relates to benzoxazoles and the use thereof to inhibit lysophosphatidic acid acyltransferase (LPAAT-) activity. The invention further relates to methods of treating cancer using said benzoxazoles. The invention also relates to methods for screening for LPAAT- activity.

US Patent:

20030100557, May 29, 2003

Filed:

Sep 6, 2002

Appl. No.:

10/236084

Inventors:

Robert Finney - Shoreline WA, US
David Leung - Mercer Island WA, US
J. Klein - Vashon WA, US
David Hollenback - Seattle WA, US
Lynn Bonham - Seattle WA, US
Scott Shaffer - Seattle WA, US
Norina Tang - Ann Arbor WA, US
Thayer White - Bellevue WA, US
John Tulinsky - Seattle WA, US
Baoqing Gong - Shoreline WA, US

Assignee:

Cell Therapeutics, Inc.

International Classification:

A61K031/5377
A61K031/53
C07D413/14
C07D413/04
C 07D 4 3/02

US Classification:

514/235800, 514/245000, 544/113000, 544/198000

Abstract:

The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase (LPAAT-) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT- activity.

US Patent:

20100189726, Jul 29, 2010

Filed:

Sep 29, 2009

Appl. No.:

12/569639

Inventors:

Lynn BONHAM - Seattle WA, US
J. Peter Klein - Vashon WA, US
Robert E. Finney - Shoreline WA, US
David M. Hollenback - Seattle WA, US
Scott A. Shaffer - Seattle WA, US
Norina M. Tang - Ann Arbor MI, US
Thayer H. White - Bellevue WA, US
David W. Leung - Mercer Island WA, US
Baoqing Gong - Shoreline WA, US
John Tulinsky - Seattle WA, US

Assignee:

Cell Therapeutics, Inc. - Seattle WA

International Classification:

A61K 31/53
C07D 251/50
C07D 405/12
C07D 251/52
A61K 39/00
A61P 35/00

US Classification:

4241781, 544208, 544209, 514245

Abstract:

The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

US Patent:

61076287, Aug 22, 2000

Filed:

Jun 3, 1998

Appl. No.:

9/090896

Inventors:

Richard D. Smith - Richland WA
Scott A. Shaffer - Seattle WA

Assignee:

Battelle Memorial Institute - Richland WA

International Classification:

H01J 4942

US Classification:

250292

Abstract:

A method and apparatus for focusing dispersed charged particles. More specifically, a series of elements within a region maintained at a pressure between 10. sup. -1 millibar and 1 bar, each having successively larger apertures forming an ion funnel, wherein RF voltages are applied to the elements so that the RF voltage on any element has phase, amplitude and frequency necessary to define a confinement zone for charged particles of appropriate charge and mass in the interior of the ion funnel, wherein the confinement zone has an acceptance region and an emmitance region and where the acceptance region area is larger than the emmitance region area.