Sean P Gallagher

US Patent:

20030064507, Apr 3, 2003

Filed:

Jul 26, 2002

Appl. No.:

10/206841

Inventors:

Sean Gallagher - Claremont CA, US
David Dorris - Austin TX, US
Lawrence Dues - Chandler AZ, US
Alan De La Cerda - Chandler AZ, US
Norb Simonson - Mesa AZ, US
Clifford Anderson - Tempe AZ, US
Phillip Franciskovich - Phoenix AZ, US
Peter Kahn - Phoenix AZ, US

International Classification:

C12M001/34

US Classification:

435/287200, 435/006000, 422/099000

Abstract:

The present invention provides microfluidic systems comprising microfluidic chambers and mixers, and methods of use. The microfluidic chambers of the present invention comprise a flexible membrane which provides efficient mixing of the solution therein. The present invention also provides a microfluidic chamber in fluidic communication with a micro-disk and a microfluidic chamber comprising a shim such that and a contiguous gap is present between a sample fluid and the chamber membrane. The microfluidic systems find use in the decrease in time for reactions occurring therein.

US Patent:

20060208199, Sep 21, 2006

Filed:

Mar 18, 2005

Appl. No.:

11/083768

Inventors:

Sean Gallagher - Claremont CA, US
Soham Mehta - Upland CA, US

International Classification:

G01J 1/58

US Classification:

250458100

Abstract:

A luminescent calibration device () is provided with the luminescent calibration device () having a housing () with a surface (). The housing () has a length (), a width (), and a thickness (). The housing () having a luminescent standard () disposed on the housing (). A method for calibrating and normalizing luminescent data across a sample and to normalize data from day to day variations is provided.

US Patent:

20100140090, Jun 10, 2010

Filed:

Dec 9, 2008

Appl. No.:

12/316183

Inventors:

Darius Kelly - Rancho Cucamonga CA, US
Sean Gallagher - Claremont CA, US

International Classification:

B01D 57/02
C25B 9/00

US Classification:

204461, 204612

Abstract:

A method and apparatus for expeditiously carrying out the preparation and imaging steps of the electrophoresis process. The apparatus of the invention includes a novel supporting surface comprising TEFLON AF that acts as a multi-function gel supporting surface which minimizes the probability of damaging the gel during transfer and provides a supporting surface that has an index of refraction lower than that of water and that of water based gel. When the TEFLON AF supporting surface is used to support the gel, or other mostly aqueous, fluorescent sample, the surface becomes a planar, aqueous core waveguide which traps the excitation light thereby increasing the efficiency of excitation.

US Patent:

20100140094, Jun 10, 2010

Filed:

Dec 9, 2008

Appl. No.:

12/316182

Inventors:

Darius Kelly - Rancho Cucamonga CA, US
Sean Gallagher - Claremont CA, US

International Classification:

G01N 23/02

US Classification:

204612

Abstract:

A gel excitation apparatus for exciting a gel that includes a container for holding an aqueous solution within which the gel can be positioned, at least one light source disposed proximate the container for irradiating the gel with radiation within at least a first wavelength band, the first wavelength band selected to excite the gel to cause the gel to emit radiation into said aqueous solution. The aqueous core of the apparatus functions not only to increase the efficiency of excitation, but also increases the contrast between excitation light and sample emission light.

US Patent:

20110308954, Dec 22, 2011

Filed:

Aug 31, 2011

Appl. No.:

13/199529

Inventors:

Darius Kelly - Rancho Cucamonga CA, US
Sean Gallagher - Claremont CA, US

International Classification:

G01N 27/26

US Classification:

204612

Abstract:

A gel excitation apparatus for exciting a gel that includes a container for holding an aqueous solution within which the gel can be positioned, at least one light source disposed whereas the light path is perpendicular to the optical axis, the container for irradiating the gel with radiation within at least a first wavelength band, the first wavelength band selected to excite the gel to cause the gel to emit radiation into said aqueous solution. The aqueous core of the apparatus has a low refractive index, thus retaining the first wavelength band selected within said aqueous core to excite the gel. Thus, the aqueous core functions not only to increase the efficiency of excitation, but also increases the contrast between excitation light and sample emission light by retaining the light within said aqueous core.