Sean T Morrison

US Patent:

20030003572, Jan 2, 2003

Filed:

Mar 5, 1999

Appl. No.:

09/263359

Inventors:

DAVID J. ANDERSON - ALTADENA CA, US
SEAN MORRISON - PASADENA CA, US

International Classification:

A61K048/00
C12N005/08

US Classification:

435/325000, 435/368000, 435/377000, 435/378000, 435/383000, 435/395000, 424/093210

Abstract:

The invention provides methods for the prospective identification, isolation, and self-renewal of neural stem cells from the mammalian peripheral nervous system and compositions of neural stem cells derived from uncultured tissue. Using flow-cytometry, neural crest derived cells of embryonic peripheral nerve were fractionated based on cell surface markers. The isolated p75Pcells from embryonic sciatic nerve were phenotypically and functionally indistinguishable from neural crest stem cells (NCSCs) previously isolated from neural tube explant cultures. Furthermore, freshly isolated p75Pcells gave rise to both neurons and glia when transplanted in vivo. Cell cycle analysis and BrdU labeling indicated that p75PNCSCs persist in the peripheral nerve by undergoing self-renewing divisions after neural crest migration has ceased.

US Patent:

20030099623, May 29, 2003

Filed:

Oct 24, 2002

Appl. No.:

10/279568

Inventors:

David Anderson - Altadena CA, US
Sean Morrison - Pasadena CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

A61K048/00
C12N005/08

US Classification:

424/093210, 435/368000

Abstract:

The invention provides methods for the prospective identification, isolation, and self-renewal of neural stem cells from the mammalian peripheral nervous system and compositions of neural stem cells derived from uncultured tissue. Using flow-cytometry, neural crest derived cells of embryonic peripheral nerve were fractionated based on cell surface markers. The isolated p75 Pcells from embryonic sciatic nerve were phenotypically and functionally indistinguishable from neural crest stem cells (NCSCs) previously isolated from neural tube explant cultures. Furthermore, freshly isolated p75 Pcells gave rise to both neurons and glia when transplanted in vivo. Cell cycle analysis and BrdU labeling indicated that p75 PNCSCs persist in the peripheral nerve by undergoing self-renewing divisions after neural crest migration has ceased.

US Patent:

20190188648, Jun 20, 2019

Filed:

Feb 21, 2019

Appl. No.:

16/282041

Inventors:

- Dana Point CA, US
SEAN MORRISON - Laguna Niguel CA, US

International Classification:

G06Q 10/10
G06F 16/9535
G06F 16/9536
G06F 16/9537
G06F 9/54

Abstract:

A matchmaking and geolocation mobile software application is designed for recruiting and professional networking. The software application allows users to have jobs and resumes attached to their public profiles, which are displayed on a map for others to see, pursue and engage. The software application can include three primary screens for user information, a map view, a user view and a list view. Users can see who is around them and the application can prioritize showing other users who have something in common. People will be able to know information about who is around them at a coffee shop, conference, or networking event prior to engaging with them in real time. Users will be able to broadcast jobs they represent to those around them and will be able to represent that job anywhere they go within the map view.

US Patent:

20190066055, Feb 28, 2019

Filed:

Dec 12, 2017

Appl. No.:

15/839603

Inventors:

- Dana Point CA, US
SEAN MORRISON - Coto de Caza CA, US

International Classification:

G06Q 10/10
H04W 4/02

Abstract:

A matchmaking and geolocation mobile software application is designed for recruiting and professional networking. The software application allows users to have jobs and resumes attached to their public profiles, which are displayed on a map for others to see, pursue and engage. The software application can include three primary screens for user information, a map view, a user view and a list view. Users can see who is around them and the application can prioritize showing other users who have something in common. People will be able to know information about who is around them at a coffee shop, conference, or networking event prior to engaging with them in real time. Users will be able to broadcast jobs they represent to those around them and will be able to represent that job anywhere they go within the map view.