Seong Gi Baek

US Patent:

62681613, Jul 31, 2001

Filed:

May 11, 1999

Appl. No.:

9/308392

Inventors:

In Suk Han - Salt Lake City UT
You Han Bae - Salt Lake City UT
Jules J. Magda - Salt Lake City UT
Seong Gi Baek - Woodbury MN

Assignee:

M-Biotech, Inc. - Salt Lake City UT

International Classification:

C12Q 154
C12M 134

US Classification:

435 14

Abstract:

A biosensor (10) has a pH-sensitive polymeric hydrogel (30) in a rigid and preferably biocompatible enclosure (20). The hydrogel (30) includes an immobilized oxidoreductase enzyme such as glucose oxidase. The oxidoreductase enzyme catalyzes a chemical reaction consuming an organic molecule and producing a byproduct. The hydrogel (30) changes its osmotic pressure in proportion to the concentration of a byproduct. By measuring the change in osmotic pressure with a pressure transducer (40), the biosensor (10) is able to accurately measure the concentration of the organic molecule without the problem of interference encountered by prior art biosensors. A battery (64) powered telemeter (60) operably engaged to the pressure transducer (40) sends a radio data signal to a receiver (66) operably attached to a computer (62).