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7207 Ibm Dr Clt 2F Legal, Charlotte, NC 28262 3315 Old Frst Rd Legal - Of 28, Lynchburg, VA 24501 Philadelphia, PA 19113 200 Great Pond Dr, Windsor, CT 06095 (610)3622000, (860)6881911, (202)4954960, (704)8052000
Sharon K Elliot Secretary
BIO INTERNATIONAL, INC
Sharon R. Elliot President, Director, Vice President
West Kendall Bookshelf, Inc
PO Box 61373, Raleigh, NC 27661 12558 N Kendall Dr, Miami, FL 33186 PO Box 566177, Miami, FL 33256
Sharon J. Elliot - Miami FL, US Paola Catanuto - Miami FL, US Scott W. Cousins - Chapel Hill NC, US
Assignee:
University of Miami - Miami FL
International Classification:
C12Q 1/02 C12N 5/00 C12N 5/02 C12N 5/06 C12N 5/08
US Classification:
435 29, 435325, 435375, 435354, 435366
Abstract:
The present invention provides isolated cultures of immortalized retinal pigmented epithelial cells. The cells retain one or more of the in vivo characteristics of non-immortalized retinal pigmented epithelial cells, including, for example, cobblestone morphology, polarization, the presence and/or expression of one or more protein markers, and a metabolic pattern typical of non-immortalized retinal pigmented epithelial cells. The present invention also provides methods of making and using immortalized retinal pigmented epithelial cells.
Mesenchymal Stem Cell-Derived Extracellular Vesicles And Uses Thereof For Treating And Diagnosing Fibrotic Diseases
- New York NY, US Sharon Elliot - Miami FL, US Robin Smith - New York NY, US
Assignee:
Spiritus Therapeutics, Inc. - New York NY
International Classification:
A61K 35/28 A61P 11/00
Abstract:
The described invention provides compositions and methods for treating a fibrotic condition in a subject. The methods include administering a therapeutic amount of a pharmaceutical composition comprising synthetic extracellular vesicles (EVs) and a pharmaceutically acceptable carrier.
Diagnostic And Therapeutic Uses Of Compositions Comprising Purified, Enriched Potent Exosomes Containing Disease-Based And Therapy Based Signature Cargo
The present disclosure provides a composition containing a purified and enriched population of potent exosomes derived from extracellular vesicles derived from mesenchymal stem cells (MSCs), a method for diagnosing a human subject aged over 50 years with an age-related chronic disease characterized by disease related dysfunction and optimally treating the subject, and a method for reprogramming a donated organ or tissue comprising a fibrotic disposition including treating the donated organ or tissue with a composition comprising purified enriched population of potent exosomes derived from extracellular vesicles derived from MSCs of a normal healthy subject.
Mesenchymal Stem Cell-Derived Extracellular Vesicles And Uses Thereof For Treating And Diagnosing Fibrotic Diseases
- New York NY, US Sharon Elliot - Miami FL, US Robin Smith - New York NY, US
Assignee:
Spiritus Therapeutics, Inc. - New York NY
International Classification:
A61K 35/28 A61P 11/00 A61K 9/00 C12Q 1/6883
Abstract:
The described invention provides compositions and methods for treating a fibrotic condition in a subject. The methods include administering a therapeutic amount of a pharmaceutical composition comprising synthetic extracellular vesicles (EVs) and a pharmaceutically acceptable carrier.
Mesenchymal Stem Cell-Derived Extracellular Vesicles And Uses Thereof For Treating And Diagnosing Fibrotic Diseases
- New York NY, US Sharon Elliot - Miami FL, US Robin Smith - New York NY, US
Assignee:
Spiritus Therapeutics, Inc. - New York NY
International Classification:
A61K 35/28 C12Q 1/6883 A61K 9/00 A61P 11/00
Abstract:
The described invention provides compositions and methods for treating a fibrotic condition in a subject. The methods include administering a therapeutic amount of a pharmaceutical composition comprising synthetic extracellular vesicles (EVs) and a pharmaceutically acceptable carrier.
University of Miami, Miller School of Medicine
Research Professor
Ivax Pharmaceuticals S.r.o. Nov 1998 - Sep 1999
Director Laboratory Operations
National Institutes of Health 1983 - 1999
Resarch
University of Miami 1983 - 1999
Professor of Surgery
Education:
The George Washington University 1990 - 1990
Doctorates, Doctor of Philosophy, Biology, Physiology
American University 1975 - 1977
Valley Stream South High School
Skills:
Science Research Medicine Biochemistry Cell Biology Medical Education Clinical Research Molecular Biology Life Sciences Cell Culture Pcr Cancer Medical Research Strategic Planning Public Speaking Microsoft Office Teaching Data Analysis Western Blotting Biotechnology Genetics Animal Models Leadership Cell Signaling Management Microscopy Retail Sales Team Leadership Translational Research Laboratory Skills Laboratory Techniques Immunohistochemistry Scientific Writing Stem Cell Research Grant Writing University Teaching Product Innovation Innovation Research Outgoing Customer Service Microsoft Powerpoint Microsoft Excel Microsoft Word Adobe Photoshop Biomarker Discovery Project Management Cross Functional Team Leadership Multidisciplinary Design Multidisciplinary Team
Interests:
Science and Technology Environment Arts and Culture Health