Sharon M Elliot

US Patent:

20220296645, Sep 22, 2022

Filed:

Mar 21, 2022

Appl. No.:

17/700283

Inventors:

- New York NY, US
Jodi Gurney - New York NY, US
Sharon Elliot - Miami FL, US

Assignee:

SPIRITUS THERAPEUTICS, INC. - New York NY

International Classification:

A61K 35/28
A61K 35/51
C12N 5/0775
C12Q 1/6883
A01N 1/02
A61K 9/50
A61P 11/00
A61P 29/00
C12N 15/113
A61P 17/02

Abstract:

The present disclosure provides a composition containing a purified and enriched population of potent exosomes derived from extracellular vesicles derived from mesenchymal stem cells (MSCs), a method for diagnosing a human subject aged over 50 years with an age-related chronic disease characterized by disease related dysfunction and optimally treating the subject, and a method for reprogramming a donated organ or tissue comprising a fibrotic disposition including treating the donated organ or tissue with a composition comprising purified enriched population of potent exosomes derived from extracellular vesicles derived from MSCs of a normal healthy subject.