Shengyuan Yang from Arlington, MA, age 53

Versatile, Flexible, And Robust Mems/Nems Sensor For Decoupled Measuring Of Three-Dimensional Forces In Air Or Liquids
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US Patent:

20140060207, Mar 6, 2014
Filed:

Aug 30, 2012
Appl. No.:

13/598661
Inventors:

Shengyuan Yang - West Melbourne FL, US
International Classification:

G01L 1/00
US Classification:

73862041
Abstract:

A force measuring device. The device comprises an x-axis sensor beam for measuring x-direction forces, a y-axis sensor beam for measuring y-direction forces, a z-axis sensor beam for measuring z-direction forces, and wherein the x-axis, y-axis and z-axis sensor beams are decoupled such that forces exerted by a specimen in one direction do not exert substantial forces on the other two sensor beams.

Substrates With Micrometer And Nanometer Scale Stiffness Patterns For Use In Cell And Tissue Culturing And A Method For Making Same
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US Patent:

20130252337, Sep 26, 2013
Filed:

Mar 21, 2012
Appl. No.:

13/426593
Inventors:

Shengyuan Yang - West Melbourne FL, US
International Classification:

C12N 5/071
B23P 17/04
US Classification:

435395, 29428
Abstract:

A substrate comprising a base, first regions having a first stiffness value and disposed above the base, second regions having a second stiffness value disposed above the base, wherein the first stiffness value is different from the second stiffness value, and wherein a portion of one or more of the first regions and a portion of one or more of the second regions is exposed on an upper surface of the substrate.

Methods And Kits For Directing Cell Attachment And Spreading
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US Patent:

20190024041, Jan 24, 2019
Filed:

Jul 18, 2017
Appl. No.:

15/652921
Inventors:

Shengyuan Yang - West Melbourne FL, US
International Classification:

C12N 5/00
C12N 5/077
C12N 5/073
Abstract:

The present disclosure provides methods, and related kits, for directing cell attachment and spreading on a substrate and inducing isotropic spreading of cells; provides methods, and related kits, for cell sorting; and further provides methods, and related kits, for guided induction of stem cell differentiation.

Methods And Kits For Guided Stem Cell Differentiation
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US Patent:

20190024052, Jan 24, 2019
Filed:

Jul 18, 2017
Appl. No.:

15/652938
Inventors:

Shengyuan Yang - West Melbourne FL, US
International Classification:

C12N 5/077
Abstract:

The present disclosure provides methods, and related kits, for directing cell attachment and spreading on a substrate and inducing isotropic spreading of cells; provides methods, and related kits, for cell sorting; and further provides methods, and related kits, for guided induction of stem cell differentiation.

Methods And Kits For Cell Sorting
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US Patent:

20190025182, Jan 24, 2019
Filed:

Jul 18, 2017
Appl. No.:

15/652928
Inventors:

Shengyuan Yang - West Melbourne FL, US
International Classification:

G01N 15/10
G01N 33/483
Abstract:

The present disclosure provides methods, and related kits, for directing cell attachment and spreading on a substrate and inducing isotropic spreading of cells; provides methods, and related kits, for cell sorting; and further provides methods, and related kits, for guided induction of stem cell differentiation.

Micro And Nano Scale Structures Disposed In A Material So As To Present Micrometer And Nanometer Scale Curvature And Stiffness Patterns For Use In Cell And Tissue Culturing And In Other Surface And Interface Applications
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US Patent:

20150072430, Mar 12, 2015
Filed:

Aug 11, 2014
Appl. No.:

14/456833
Inventors:

Shengyuan Yang - West Melbourne FL, US
International Classification:

C12N 5/077
C12N 5/00
US Classification:

435396, 435402
Abstract:

A structure for use in cell and tissue culturing and in other surface and interface applications. The structure comprises a first material layer defining one or more surface features therein disposed randomly or in a pattern, the one or more surface features having the same or different sizes and cross sectional shapes, a second material layer disposed in or on the one or more surface features, a microstructure disposed in or on the one or more surface features and at least partially embedded and immobile within the second material layer, the microstructure presenting a curvature and a stiffness value and protruding above an upper surface of the second material, a size of the microstructure between 1 nanometer and 10 millimeters, and the structure for use in cell and tissue culturing and in other surface and interface applications wherein a cell grows on the microstructure.

Micro And Nano Glass Balls Embedded In A Gel Presenting Micrometer And Nanometer Scale Curvature And Stiffness Patterns For Use In Cell And Tissue Culturing And A Method For Making Same
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US Patent:

20140147918, May 29, 2014
Filed:

Nov 25, 2012
Appl. No.:

13/656808
Inventors:

Shengyuan Yang - West Melbourne FL, US
International Classification:

C12N 5/071
US Classification:

435357
Abstract:

A substrate for use in culturing cells or tissues. The substrate comprises a gel, one or more microstructures partially embedded within a surface of the gel, the one or more microstructures presenting two different curvatures or presenting two different stiffness values or presenting a combination of different curvatures and different stiffness values, wherein the microstructures are disposed at defined locations within the surface of the gel, and wherein the cells and tissues are cultured on an exposed surface of the microstructures.

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Location:

Melbourne, FL

Industry:

Higher Education

Work:

Florida Institute of Technology
Assistant Professor

Shengyuan Yang