Sherrie L Sanda from 919 Iroquois Run, Macedonia, OH 44056, age 56, Phone: (330)4676780

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Position:

Scientist 1 at usb

Location:

Cleveland/Akron, Ohio Area

Industry:

Research

Work:

usb
Scientist 1

Compositions And Methods For The Synthesis And Subsequent Modification Of Uridine-5′-Diphosphosulfoquinovose (Udp-Sq)
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US Patent:

7479387, Jan 20, 2009
Filed:

Oct 31, 2006
Appl. No.:

11/590541
Inventors:

Christoph Benning - East Lansing MI, US
Sherrie Lea Sanda - Haslett MI, US
Bin Yu - East Lansing MI, US
Assignee:

Michigan State University - Lansing MI
International Classification:

C12N 1/20
C12N 15/00
C12N 5/00
C12Q 1/00
C12Q 1/68
C12P 21/04
C07H 21/04
C12Q 1/48
C12N 9/00
US Classification:

4352523, 435 4, 435 6, 435 691, 435 711, 435183, 435193, 435 15, 4353201, 435440, 435410, 536 232
Abstract:

The present invention is directed to compositions and methods related to the synthesis and modification of uridine-5′-diphospho-sulfoquinovose (UDP-SQ). In particular, the methods of the present invention comprise the utilization of recombinant enzymes from , UDP-glucose, and a sulfur donor to synthesize UDP-SQ, and the subsequent modification of UDP-SQ to form compounds including, but not limited to, 6-sulfo-α-D-quinovosyl diaclyglycerol (SQDG) and alkyl sulfoquinovoside. The compositions and methods of the invention provide a more simple, rapid means of synthesizing UDP-SQ, and the subsequent modification of UDP-SQ to compounds including, but not limited to, SQDG.

Compositions And Methods For The Synthesis And Subsequent Modification Of Uridine-5′-Diphosphosulfoquinovose (Udp-Sq)
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US Patent:

7226764, Jun 5, 2007
Filed:

Nov 8, 2000
Appl. No.:

09/709020
Inventors:

Christoph Benning - East Lansing MI, US
Sherrie Lea Sanda - Haslett MI, US
Bin Yu - East Lansing MI, US
Assignee:

The Board of Trustees Operating Michigan State University - East Lansing MI
International Classification:

C12P 7/00
C12N 9/00
C12N 9/10
C12N 1/20
C12N 15/00
C12Q 21/04
C07H 21/04
C12Q 1/00
C12Q 1/68
C12Q 1/48
US Classification:

435132, 435183, 435193, 435 4, 435 6, 435 15, 435252, 4353201, 435 691, 435 711, 435440, 536 232, 536 237
Abstract:

The present invention is directed to compositions and methods related to the synthesis and modification of uridine-5′-diphospho-sulfoquinovose (UDP-SQ). In particular, the methods of the present invention comprise the utilization of recombinant enzymes from , UDP-glucose, and a sulfur donor to synthesize UDP-SQ, and the subsequent modification of UDP-SQ to form compounds including, but not limited to, 6-sulfo-α-D-quinovosyl diaclyglycerol (SQDG) and alkyl sulfoquinovoside. The compositions and methods of the invention provide a more simple, rapid means of synthesizing UDP-SQ, and the subsequent modification of UDP-SQ to compounds including, but not limited to, SQDG.

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Sherrie L Sanda