Sherry T Hikita from Livermore, CA, age 55

Biosynthetic Oncolytic Molecules And Uses Therefor
view source
US Patent:

20050048614, Mar 3, 2005
Filed:

Jul 28, 2004
Appl. No.:

10/900512
Inventors:

Samy Ashkar - New Haven CT, US
Sherry Hikita - Santa Barbara CA, US
Ghassan Dehni - Boston MA, US
International Classification:

C07H021/04
C12N009/24
C12N009/64
US Classification:

435069100, 435200000, 435226000, 435320100, 435325000, 536023200
Abstract:

Biosynthetic oncolytic molecules including an apoptotic domain derived from osteopontin have been developed which are capable of promoting cellular apoptosis.

Biosynthetic Oncolytic Molecules And Uses Therefor
view source
US Patent:

20040034193, Feb 19, 2004
Filed:

Aug 28, 2002
Appl. No.:

10/220107
Inventors:

Samy Ashkar - Boston MA, US
Sherry Hikita - Santa Barbara CA, US
Ghassan Dehni - Boston MA, US
International Classification:

A61K038/17
C07K014/47
US Classification:

530/350000, 514/012000
Abstract:

Novel biosynthetic oncolytic molecules are provided. The biosynthetic oncolytic molecules include functional domains derived from osteopontin. Preferred biosynthetic oncolytic molecules include an apoptotic domain derived from osteopontin. The oncolytic molecules of the present invention are capable of promoting cellular apoptosis. Accordingly, therapeutic uses are disclosed which feature the biosynthetic oncolytic molecules of the present invention.

Biocompatible Substrate For Facilitating Interconnections Between Stem Cells And Target Tissues And Methods For Implanting Same
view source
US Patent:

20190151499, May 23, 2019
Filed:

Dec 17, 2018
Appl. No.:

16/222918
Inventors:

- Los Angeles CA, US
- Pasadena CA, US
- Oakland CA, US
David R. Hinton - Venice CA, US
Robert H. Grubbs - South Pasadena CA, US
Dennis O. Clegg - Ventura CA, US
Lincoln Vallance Johnson - Santa Barbara CA, US
Sherry T. Hikita - Pleasanton CA, US
Assignee:

University of Southern California - Los Angeles CA
California Institute of Technology - Pasadena CA
The Regents of the University of California - Oakland CA
International Classification:

A61L 27/18
A61K 47/34
A61K 35/30
A61L 27/38
A61L 27/56
A61K 35/545
A61K 9/00
Abstract:

Disclosed herein are substrates for cell delivery to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide seeded cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.

Methods Of Culturing Retinal Pigmented Epithelium Cells, Including Xeno-Free Production, Rpe Enrichment, And Cryopreservation
view source
US Patent:

20180087029, Mar 29, 2018
Filed:

Nov 17, 2017
Appl. No.:

15/816912
Inventors:

- Oakland CA, US
Sherry Hikita - Santa Barbara CA, US
Lincoln Johnson - Santa Barbara CA, US
Liane Miller - San Francisco CA, US
Marlene Tsie - Santa Barbara CA, US
Chelsea Presbrey - Flagstaff AZ, US
Lisa Conti - Goleta CA, US
Michelle Maloney - Santa Barbara CA, US
David Hinton - Venice Beach CA, US
Qirui Hu - Santa Barbara CA, US
International Classification:

C12N 5/079
Abstract:

The production of high quality retinal pigmented epithelium (RPE) cells is necessary for research and potential therapeutic uses. Especially desirable are methods for the production of RPE cells using xeno-free culture conditions. Disclosed herein are novel methods for the production of RPE cells from pluripotent cells with high yields, including xeno-free production methods. Also provided are methods of efficiently isolating RPE cells from cultures containing heterogeneous cell types, allowing for substantially pure RPE cell cultures to be established. Additionally, novel methods for the cryopreservation of RPE cells are provided.

Biocompatible Substrate For Facilitating Interconnections Between Stem Cells And Target Tissues And Methods For Implanting Same
view source
US Patent:

20150147377, May 28, 2015
Filed:

Jun 25, 2014
Appl. No.:

14/314994
Inventors:

Mark Humayun - Glendale CA, US
Ashish Ahuja - Los Angeles CA, US
Yu-Chong Tai - Pasadena CA, US
David Hinton - Venice CA, US
Robert Grubbs - South Pasadena CA, US
Dennis Clegg - Ventura CA, US
Lincoln Vallance Johnson - Santa Barbara CA, US
Sherry T. Hikita - Santa Barbara CA, US
International Classification:

A61L 27/18
A61L 27/56
US Classification:

424422
Abstract:

Disclosed herein are substrates for cell delivery to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide seeded cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.

Instruments And Methods For The Implantation Of Cell-Seeded Substrates
view source
US Patent:

20150032207, Jan 29, 2015
Filed:

Apr 27, 2012
Appl. No.:

14/114160
Inventors:

Mark Humayun - Glendale CA, US
Ashish Ahuja - New York NY, US
Yu-Chong Tai - Pasadena CA, US
Robert Grubbs - Pasadena CA, US
Rodrigo Brant - Los Angeles CA, US
Trent Wells - Altadena CA, US
Lincoln Vallance Johnson - Santa Barbara CA, US
Sherry T. Hikita - Santa Barbara CA, US
David Hinton - Venice CA, US
International Classification:

A61B 17/29
A61F 2/46
C12N 5/079
A61M 5/14
A61F 9/00
A61F 2/14
A61M 1/12
US Classification:

623 31, 623 2372, 623 41, 623 1611
Abstract:

Disclosed herein are instruments and methods for delivery of substrates, including cell-seeded substrates, to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.

Sherry T Hikita