- Los Angeles CA, US Alka POTDAR - Cumming GA, US Shishir DUBE - Los Angeles CA, US
International Classification:
C07K 16/24 G01N 33/68 C12Q 1/6883
Abstract:
Provided herein are methods, systems and kits for use in identifying a subject with an increased risk of developing severe forms of inflammatory bowel disease (IBD), based at least in part, on an expression of one or more biomarkers detected in a biological sample obtained from the subject. Also provided are methods, systems and kits for treating, or optimizing the treatment for, the IBD based, at least in part, on the expression the one or more biomarkers. In some embodiments, the one or more biomarkers is angiotensin-converting enzyme 2 (ACE2), the host receptor for severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2).
Methods And Systems For Characterizing Severe Crohn's Disease
- Los Angeles CA, US Dalin LI - Walnut CA, US Phillip GU - Los Angeles CA, US Shishir DUBE - Los Angeles CA, US
International Classification:
C12Q 1/6883
Abstract:
The present disclosure describes methods, devices and systems of diagnosing, prognosing, and treating subjects with moderate to severe forms of Crohn's disease (CD) that is characterized by stricturing and internal penetrating disease phenotypes. Also described are methods and kits for characterizing a subtype of CD, and identifying a subject as being suitable for a therapy to treat the CD.
Resumes
Project Manager And Data Scientist And Specialist Business Analyst
Amgen
Project Manager and Data Scientist and Specialist Business Analyst
Amgen Apr 2009 - Jan 2012
Senior Business Analyst and Data Scientist
Siemens Healthcare Jun 2008 - Oct 2008
Intern
Education:
University of California, Los Angeles 2004 - 2009
Doctorates, Doctor of Philosophy, Biomedical Engineering, Philosophy
University of Pennsylvania 2003 - 2004
University of Pennsylvania 1999 - 2003
Bachelor of Science In Engineering, Bachelors, Bioengineering
North Carolina School of Science and Mathematics 1997 - 1999
Skills:
Image Analysis Data Mining Medical Imaging Bioinformatics Machine Learning Biotechnology Lifesciences Biomedical Engineering Pattern Recognition Digital Imaging Cell Healthcare Pharmaceutical Industry Statistical Modeling Molecular Biology Fda Oncology Neuroscience R&D Clinical Trials Cross Functional Team Leadership Data Science Business Analysis Project Management Life Sciences Research and Development Drug Discovery