Shu Chieh Chang

US Patent:

7195623, Mar 27, 2007

Filed:

Mar 21, 2002

Appl. No.:

10/473285

Inventors:

Andrew Christopher Burroughs - Kenosha WI, US
Shu Kun Chang - Evanston IL, US
Mark James Fisher - Highland Park IL, US
Benjamin L Rush - Evanston IL, US
Richard Charles Thorne - Indianapolis IN, US

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61M 5/32
A61B 19/00

US Classification:

604411, 604415, 604232, 604187

Abstract:

A kit and needle assembly for reconstituting a quantity of a lyophilized pharmaceutical. The kit of the invention may include a reconstituting appliance having a non-transparent needle covering portion with a hollow adapted to receive the inserted stoppered end of the injection pen cartridge, which needle covering portion extends around a side-firing cannula to hide the cannula from side view. A shiftable alignment member retained within the needle covering portion at a first axial position, and shiftable to a second axial position when abutted by the injection pen cartridge during its insertion, may be included. The kit includes an injection pen cartridge including a barrel filled with a quantity of a lyophilized drug, a slidable plunger used during pen operation to eject the reconstituted drug, and a stopper penetrable by the cannula during drug reconstituting. The needle assembly of the invention may include a cannula defining an axial passage therethrough in communication with a reservoir of diluent fluid. The distal end of the cannula terminates in a closed piercing tip, and is provided with a side port, in communication with the axial passage, which is configured to direct fluid passing through it in a direction diverging from the axis of the cannula.