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Languages
English • German • French • Swiss German • Indonesian • Chinese • Russian • Korean
Industries
International Trade and Development
Resumes
International Trade Counsel | Market Access Advisor
Asian Development Bank - Manila Jul 2012 - Apr 2013
Team Leader
Institute of International Economic Law - Washington D.C. Metro Area Aug 2011 - May 2012
Fellow
The ASEAN Secretariat - Jakarta Indonesia Jun 2011 - Aug 2011
Senior Trade Advisor
University of Stellenbosch - Stellenbosch, South Africa Jul 2009 - Nov 2009
Visiting Lecturer
Trade Law Chambers - Cape Town Area, South Africa Jan 2008 - May 2009
Senior Trade Advisor - Legal
Education:
Georgetown University Law Center 2011 - 2012
LL.M., International Economic Law
Universiteit Leiden 2008 - 2012
PhD, International Economic Law
National University of Singapore 2006 - 2007
Université de Fribourg/Universität Freiburg 1992 - 1998
Lic Iur, Law and European Law
University of Berne
Skills:
Central Asia Former Soviet Union Sub-Saharan Africa Eastern Europe Africa Government Research Technical Assistance International Law Intellectual Property Policy Capacity Building International Trade International Trade Law Public International Law International Relations International Development English Policy Analysis Government Relations Public Policy Program Management French Teaching Writing Governance EU Translation Proposal Writing Microsoft Office Diplomacy Foreign Investment German International Business Change Management Dispute Resolution Report Writing Corporate Law Organizational Development Qualitative Research WTO NAFTA Free Trade Agreements Regulatory Research ASEAN Trade Negotiations
Languages:
English German French Swiss German Indonesian Chinese Russian Korean
The present invention relates to HLA-A*02-restricted cellular epitopes within the VP1 polypeptide of a human polyomavirus, BK virus, which is associated with polyomavirus-associated nephropathy in kidney transplant patients. Preferred peptides correspond to amino acids residues 107-116, 108-116 and 44-52 of BKV VP1, and are processed in vivo in natural infection with BKV. Effector T cell populations stimulated by the peptides represent functional CTLs as assessed by cytotoxicity and cytokine production, and are reactive against cells presenting both the BKV peptides above and the JC virus homolog sequences.
The present invention relates to HLA-A*02-restricted cellular epitopes within the VP1 polypeptide of human polyomaviruses, which are useful as diagnostic reagents for virus infection. Preferred peptides correspond to amino acids residues 107-116, 108-116 and 44-52 of BKV VP1, and are processed in vivo in natural infection with BKV. Effector T cell populations stimulated by the peptides represent functional CTLs as assessed by cytotoxicity and cytokine production, and are reactive against cells presenting both the BKV peptides above and the JC virus homolog sequences.
- Basel, CH - Philadelphia PA, US Joseph A. Fraietta - Williamstown NJ, US Simon Lacey - Media PA, US Jan J. Melenhorst - Cherry Hill NJ, US Carl H. June - Merion Station PA, US
The invention provides methods for manufacturing optimized CAR T cell therapies and uses thereof. Specifically, the invention provides parameters that can be measured, e.g., evaluated, to manufacture CAR T cell therapies with optimized properties. The invention further provides methods of use in connection with said optimized CART cells.
Combination Therapies Of Chimeric Antigen Receptors And Pd-1 Inhibitors
- Basel, CH - Philadelphia PA, US Jennifer Brogdon - Sudbury MA, US John Scott Cameron - Belmont MA, US William Chou - Maplewood NJ, US Stephan Grupp - Havertown PA, US Randi Isaacs - Basking Ridge NJ, US Carl H. June - Merion Station PA, US Simon Lacey - Media PA, US Shannon Maude - Conshohocken PA, US Jan J. Melenhorst - Cherry Hill NJ, US Stephen Shuster - Springfield PA, US
Assignee:
Novartis AG - Basel The Trustees of the University of Pennsylvania - Philadelphia PA
Provided are compositions and methods for treating diseases, e.g., cancers, e.g., diseases associated with expression of an antigen, e.g., CD 19, comprising administering a cell that expresses a chimeric antigen receptor (CAR) specific to the antigen, e.g., CD19, in combination with a PD-1 inhibitor.
Biomarkers Predictive Of Cytokine Release Syndrome
Alfred Garfall - Wallingford PA, US Alex Ganetsky - Philadelphia PA, US Saar Gill - Philadelphia PA, US Simon Lacey - Media PA, US Jan J. Melenhorst - Cherry Hill NJ, US David Teachey - Rutledge PA, US - Philadelphia PA, US
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
The present disclosure relates to the identification and use of biomarkers (e.g., analytes, analyte profiles, or markers (e.g., gene expression and/or protein expression profiles)) with clinical relevance to cytokine release syndrome (CRS).