Srividya Akella

US Patent:

20130280793, Oct 24, 2013

Filed:

Apr 23, 2012

Appl. No.:

13/453235

Inventors:

Robert Christopher Brown - San Diego CA, US
Jennifer Coppersmith - San Diego CA, US
Prachee Prakash - San Diego CA, US
Srividya Akella - San Diego CA, US
Rekha Seshadri - San Diego CA, US

Assignee:

ExxonMobil Research and Engineering Company - Annandale NJ

International Classification:

C12N 1/13
C12N 15/53

US Classification:

4352572, 536 232

Abstract:

The invention relates to methods for producing lipids such as fatty acid products in recombinant host cells engineered to express a non-native gene encoding a dehydrogenase. The recombinant microorganisms are able to proliferate at a higher rate as compared with microorganisms that do not express a non-native dehydrogenase gene, and cultures of microorganisms that are engineered for lipid production and that express a non-native dehydrogenase produce more lipid than cultures of control microorganisms that do not include a non-native dehydrogenase gene.

US Patent:

20130023035, Jan 24, 2013

Filed:

Jun 28, 2012

Appl. No.:

13/536345

Inventors:

Vincent A. Bielinski - San Diego CA, US
Nicholas Bauman - San Diego CA, US
Kate Lyons Boyd - Encinitas CA, US
Srividya Akella - San Diego CA, US
Stanley Bower - San Diego CA, US
Paul G. Roessler - Bonita Springs FL, US

Assignee:

ExxonMobil Research and Engineering Company - Annandale NJ

International Classification:

C12N 1/21
C12N 1/13

US Classification:

4352523, 4352572

Abstract:

The present invention relates to the regulation of a toxin and/or antitoxin genes in a genetically engineered microorganism, such as cyanobacterial or eukaryotic algal strains, in particular for preventing unintentional and/or uncontrolled spread of the microorganisms. The present invention also includes methods of controlling the growth and/or survival of the engineered microorganism

US Patent:

20150094209, Apr 2, 2015

Filed:

Dec 6, 2013

Appl. No.:

14/099682

Inventors:

- La Jolla CA, US
Leah Soriaga - San Diego CA, US
Srividya Akella - San Diego CA, US

Assignee:

Synthetic Genomics, Inc. - La Jolla CA

International Classification:

C12N 15/82
C12Q 1/68

US Classification:

506 2, 536 231, 4353201, 435471, 435455, 435468, 435 691, 435 913, 435 9131, 435189, 435183, 435199, 435194, 435196, 435233, 435232

Abstract:

The present invention provides autonomous replication sequences (ARSs) isolated from that support the replication of episomal DNA molecules (EDMs) in eukaryotic cells. The ARSs and EDMs provided herein can be used for expressing genes in organisms including algae and heterokonts.