Stephanie M Ott

US Patent:

20120329749, Dec 27, 2012

Filed:

Jun 20, 2012

Appl. No.:

13/528393

Inventors:

Stephen Albert Lonnie Smith - Alexandria LA, US
Jeffrey Lynn Barringer - Lowell AR, US
Craig Jay Brown - Fayetteville AR, US
Gilberto Sanchez - Cecil AL, US
Stephanie Michelle Ott - Prattville AL, US
Brian Buell - Fayetteville AR, US

International Classification:

A61K 31/714
A61P 3/06
A61P 25/00
A61P 25/06
A61P 21/00
A61P 3/00
A61P 15/10

US Classification:

514 52

Abstract:

The present invention relates to methods of treating, preventing, and/or improving disorders and conditions related to certain metabolic abnormalities including methods of improving blood lipid profiles and muscle recovery and repair in athletes, methods of treating fibromyalgia, erectile dysfunction, diseases associated with certain HLA-DQ gene alleles and/or gluten intolerance, including Celiac Disease, headaches and migraines, as well as idiopathic neuropathy, inability to sleep, inability to concentrate, and/or neurological development issues in children, the methods involving the administration of one or more downstream folate compounds and optionally methyl-B12. In one particular embodiment, the method comprises administration of L-methylfolate. In certain embodiments, the method further involves identifying a subject organism with a malfunction in one or more of the folate or B4 cycles. In certain embodiments, such a malfunction is one or more of the C677T and A1298C genetic polymorphisms.