Stephen Michael Berry

US Patent:

7258869, Aug 21, 2007

Filed:

Feb 3, 2000

Appl. No.:

09/497422

Inventors:

Stephen A. Berry - Hollister CA, US
Pamela J. Fereira - Redwood City CA, US
Houdin Dehnad - El Granada CA, US
Anna Muchnik - Belmont CA, US

Assignee:

Alza Corporation - Mountain View CA

International Classification:

A61F 13/00
A61F 2/00
A61K 9/70
A01N 25/00

US Classification:

424422, 424449, 424423, 514937

Abstract:

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10reciprocal second.

US Patent:

7919109, Apr 5, 2011

Filed:

Mar 11, 2008

Appl. No.:

12/075435

Inventors:

Stephen A. Berry - Hollister CA, US
Pamela J. Fereira - Redwood City CA, US
Houdin Dehnad - El Granada CA, US
Anna Muchnik - Belmont CA, US

Assignee:

Intarcia Therapeutics, Inc. - Hayward CA

International Classification:

A61F 2/00
A61K 47/00
A61K 47/30

US Classification:

424423, 514772, 5147723, 514784, 514785

Abstract:

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10reciprocal second.

US Patent:

8048438, Nov 1, 2011

Filed:

Mar 17, 2008

Appl. No.:

12/077117

Inventors:

Stephen A. Berry - Hollister CA, US
Pamela J. Fereira - Redwood City CA, US
Houdin Dehnad - El Granada CA, US
Anna Muchnik - Belmont CA, US

Assignee:

Intarcia Therapeutics, Inc. - Hayward CA

International Classification:

A61F 13/00

US Classification:

424422, 4241301, 424424, 424 91, 4352865, 4352881

Abstract:

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10reciprocal second.

US Patent:

8173150, May 8, 2012

Filed:

Mar 8, 2011

Appl. No.:

13/043288

Inventors:

Stephen A. Berry - Hollister CA, US
Pamela J. Fereira - Redwood City CA, US
Houdin Dehnad - El Granada CA, US
Anna Muchnik - Belmont CA, US

Assignee:

Intarcia Therapeutics, Inc. - Hayward CA

International Classification:

A61F 2/00
A61K 47/00
A61K 47/30

US Classification:

424423, 514772, 5147723, 514784, 514785

Abstract:

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10reciprocal second.

US Patent:

8268341, Sep 18, 2012

Filed:

Apr 23, 2012

Appl. No.:

13/454063

Inventors:

Stephen A. Berry - Hollister CA, US
Pamela J. Fereira - Redwood City CA, US
Houdin Dehnad - El Granada CA, US
Anna Muchnik - Belmont CA, US

Assignee:

Intarcia Therapeutics, Inc. - Hayward CA

International Classification:

A61F 2/00
A61K 47/30
A61K 47/00

US Classification:

424423, 5147723, 514784, 514785, 514772

Abstract:

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10reciprocal second.

US Patent:

8372424, Feb 12, 2013

Filed:

Aug 28, 2012

Appl. No.:

13/596971

Inventors:

Stephen A. Berry - Hollister CA, US
Pamela J. Fereira - Redwood City CA, US
Houdin Dehnad - El Granada CA, US
Anna Muchnik - Belmont CA, US

Assignee:

Intarcia Therapeutics, Inc. - Hayward CA

International Classification:

A61F 2/00
A61K 9/14
A61K 47/30
A61K 47/00

US Classification:

424423, 424489, 5147723, 514784, 514785, 514772

Abstract:

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10reciprocal second.

US Patent:

20030108609, Jun 12, 2003

Filed:

Dec 12, 2002

Appl. No.:

10/319277

Inventors:

Stephen Berry - Hollister CA, US
Pamela Fereira - Redwood City CA, US
Houdin Dehnad - El Granada CA, US
Anna Muchnik - Belmont CA, US

International Classification:

A61K009/14

US Classification:

424/486000

Abstract:

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10reciprocal second.

US Patent:

20040224903, Nov 11, 2004

Filed:

Dec 19, 2003

Appl. No.:

10/742730

Inventors:

Stephen Berry - Hollister CA, US
Pamela Fereira - Santa Clara CA, US
Gunjan Junnarkar - Palo Alto CA, US
Michael Desjardin - Sunnyvale CA, US

International Classification:

A61K031/70

US Classification:

514/023000

Abstract:

The present invention provides a suspension vehicle and suspension formulations deliverable from an implantable delivery device. In particular, the suspension vehicle of the present invention allows the formulation of beneficial agent suspensions that are stable over time at ambient and physiological temperatures. In addition, the beneficial agent suspensions formed using the suspension vehicle of the present invention allow controlled delivery of beneficial agent from an implanted delivery device over sustained periods of time, even when such delivery occurs at low-flow rates, through a small-diameter delivery channel. Also included in the present invention are implantable delivery devices.