Stephen E Erickson

US Patent:

20210341477, Nov 4, 2021

Filed:

Apr 30, 2021

Appl. No.:

17/245584

Inventors:

- Burlington NC, US
Minh Mindy Bao Nguyen - Shoreview MN, US
Stephen Erickson - White Bear Township MN, US
Jose Gil - Winnetka CA, US

International Classification:

G01N 33/569
G01N 33/68

Abstract:

Disclosed are compositions, methods and systems for detecting MRSA, for example MRSA nasal colonization. In certain embodiments, the methods use bacteriophage-based amplification of the signal in detection of bacteria and other microorganisms to detect MRSA. The methods for detecting MRSA may include preparing an assay comprising a selective agent and a cocktail comprising at least two different types of recombinant bacteriophages, incubating the sample in the assay, capturing an indicator protein product, and detecting an indicator protein product produced by the recombinant bacteriophage, wherein positive detection of the indicator protein product indicates that MRSA is present in the sample.

US Patent:

20210331978, Oct 28, 2021

Filed:

Mar 24, 2021

Appl. No.:

17/210789

Inventors:

- Chicago IL, US
Annamaria Vilinska - Chicago IL, US
Alfred Li - Naperville IL, US
Blair C. Walker - Timmins, CA
Te Hua Lau - Glenview IL, US
Stephen P. Erickson - Imperial CA, US
Jose Luis Carrazco - Imperial CA, US
Angel Arturo Rueda - El Centro CA, US

International Classification:

C04B 28/14
C04B 38/10
C04B 24/42
C04B 11/00
C04B 18/16
C04B 111/00

Abstract:

A method for making a gypsum board including:

US Patent:

20210238559, Aug 5, 2021

Filed:

Feb 8, 2021

Appl. No.:

17/170357

Inventors:

- Burlington NC, US
Stephen Erickson - White Bear Township MN, US
Ben Barrett Hopkins - Sherman Oaks CA, US
Minh Mindy Bao Nguyen - Shoreview MN, US
Dwight Lyman Anderson - Minneapolis MN, US

Assignee:

Laboratory Corporation of America Holdings - Burlington NC

International Classification:

C12N 7/00
C12Q 1/10
C12Q 1/6804
C12Q 1/689

Abstract:

Disclosed herein are methods and systems for rapid detection of microorganisms in a sample. A genetically modified bacteriophage is also disclosed which comprises an indicator gene in the late gene region. The specificity of the bacteriophage, such as CBA120, allows detection of a specific microorganism, such as O157:H7, and an indicator signal may be amplified to optimize assay sensitivity.

US Patent:

20210079443, Mar 18, 2021

Filed:

Apr 24, 2019

Appl. No.:

17/050115

Inventors:

- Burlington NC, US
STEPHEN ERICKSON - White Bear Township MN, US
MINH MINDY BAO NGUYEN - Shoreview MN, US
DWIGHT LYMAN ANDERSON - Minneapolis MN, US

International Classification:

C12Q 1/14
C12Q 1/66

Abstract:

Disclosed herein are methods and systems for detection of microorganisms in a sample and the utilization of such methods for selecting and monitoring therapies. The specificity of indicator bacteriophage, such as -specific bacteriophage, allows detection of a specific microorganism, such as and the indicator signal may be amplified to optimize assay sensitivity.

US Patent:

20200399614, Dec 24, 2020

Filed:

Jun 18, 2020

Appl. No.:

16/905607

Inventors:

- Burlington NC, US
Dwight L Anderson - Minneapolis MN, US
Stephen Erickson - White Bear Township MN, US
Minh Mindy Bao Nguyen - Shoreview MN, US

International Classification:

C12N 7/00
C12R 1/01

Abstract:

Disclosed herein are methods for the production of mutant bacteriophages with altered host range. Additionally, disclosed herein are methods and systems for rapid detection of microorganisms such as spp. in a sample. A genetically modified bacteriophage is also disclosed which comprises an indicator gene in the late gene region. The specificity of the bacteriophage, such as -specific bacteriophage, allows detection of a specific microorganism, such as spp. and an indicator signal may be amplified to optimize assay sensitivity.

US Patent:

20190010534, Jan 10, 2019

Filed:

Jul 3, 2018

Appl. No.:

16/026462

Inventors:

- Burlington NC, US
Dwight L. Anderson - Minneapolis MN, US
Jose S. Gil - Winnetka CA, US
Stephen E. Erickson - White Bear Township MN, US
Matthew J. Brown - Burlington NC, US

International Classification:

C12Q 1/14
C12Q 1/10
C12Q 1/66
C12Q 1/06

Abstract:

Disclosed herein are methods and systems for rapid detection of antibiotic resistance of a microorganism in a sample. A modified recombinant phage is also disclosed which comprises an indicator gene in the late gene region. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.

US Patent:

20170121688, May 4, 2017

Filed:

Jan 18, 2017

Appl. No.:

15/409258

Inventors:

- Burlington NC, US
Stephen Erickson - White Bear Township MN, US
Ben Barrett Hopkins - Sherman Oaks CA, US
Minh Mindy Bao Nguyen - Shoreview MN, US
Dwight Lyman Anderson - Minneapolis MN, US

International Classification:

C12N 7/00
C12Q 1/10

Abstract:

Disclosed herein are methods and systems for rapid detection of microorganisms in a sample. A genetically modified bacteriophage is also disclosed which comprises an indicator gene in the late gene region. The specificity of the bacteriophage, such as CBA120, allows detection of a specific microorganism, such as O157:H7, and an indicator signal may be amplified to optimize assay sensitivity.