Stephen A Levine

US Patent:

20100004345, Jan 7, 2010

Filed:

Jun 30, 2009

Appl. No.:

12/495747

Inventors:

Charles A. Signorino - Norristown PA, US
Terry L. Smith - Norristown PA, US
Stephen Levine - Norristown PA, US

International Classification:

A61K 47/32

US Classification:

5147725

Abstract:

The invention generally relates to film coating compositions and processes for film coating pharmaceutical, nutraceutical, and food products. One film coating composition includes a shellac in an aqueous solution; a hydrolyzed starch product; an optional plasticizer; and a coating resin. The coating resin may be one or more of polyvinyl pyrrolidone, polyvinyl alcohol, and poly(vinyl pyrrolidone-vinyl acetate). The shellac, hydrolyzed starch product, plasticizer and coating resin comprise the solids in the composition.

US Patent:

20110269850, Nov 3, 2011

Filed:

Apr 28, 2010

Appl. No.:

12/769645

Inventors:

Charles A. Signorino - Norristown PA, US
Terry L. Smith - Norristown PA, US
Stephen Levine - Norristown PA, US

International Classification:

A61K 47/46

US Classification:

514778

Abstract:

The field of the invention generally relates to a shellac-based enteric coating with a reliable and consistent dissolution profile in both acid and neutral environments based on the selective choice of coating excipients used with the shellac. The enteric coating formulation includes a shellac, a maltrin, sodium alginate, one or more plasticizers, and optionally talc. The shellac is present in a range of approximately 40% to 60% w/w % and has an acid number of between 71 and 73. The maltrin is present in a range of approximately 15% to 30% w/w %. The sodium alginate is present in a range of approximately 15% to 30% w/w %. The one or more plasticizers are present in a range of approximately 2% to 20% w/w %. The optional talc is present in a range of 0% to 10%.

US Patent:

20200084281, Mar 12, 2020

Filed:

Sep 12, 2018

Appl. No.:

16/129517

Inventors:

- San Francisco CA, US
Colin Jackson - Brooklyn NY, US
Eric James Malm - Daly City CA, US
Stephen C. Levine - Ann Arbor MI, US
Zachary D. Robinson - San Francisco CA, US

International Classification:

H04L 29/08
H04L 29/06

Abstract:

Methods, systems, and computer programs encoded on computer storage media, for binding service credentials to an application. One example system receives a service bind request for an application in a cloud application platform. The service bind request includes a request to bind a service provided by a service host in the cloud application platform. The service bind request specifies (i) an identifier for the service and (ii) a unique identifier for the application. The system receives, from the service host, credentials for the application to access the service. The system provides the credentials to a secure credential hub installed on the cloud application platform. The secure credential hub stores the credentials in association with a credential location identifier. The system grants, to the unique identifier for the application, read access to the credential location identifier. The system stores the credential location identifier as application metadata for the application.

US Patent:

20150056275, Feb 26, 2015

Filed:

Mar 6, 2013

Appl. No.:

14/383462

Inventors:

- San Diego CA, US
John Christopher Carter - Keswick, CA
Dana Elaine Moseson - Haverton PA, US
Stephen Paul Levine - Norristown PA, US

Assignee:

SANTARUS, INC. - Raleigh NC

International Classification:

A61K 9/20
A61K 9/48
A61K 31/58
A61K 9/28
A61K 31/606

US Classification:

424461, 424480, 424465, 514166

Abstract:

Described are controlled-release solid dosage forms of mesalamine. In one aspect of the invention the controlled-release solid dosage forms of mesalamine are capsules comprising a plurality of coated mini-tablets. Another aspect of the invention relates to a method of treating a patient suffering from inflammatory bowel disease, comprising the step of administering to the patient a therapeutically effective amount of the solid dosage form. The invention also relates to methods of inducing remission of inflammatory bowel disease and maintaining remission of inflammatory bowel disease. In certain aspects, the inflammatory bowel disease is ulcerative colitis or Crohn's disease.

US Patent:

20140105976, Apr 17, 2014

Filed:

Oct 11, 2013

Appl. No.:

14/052302

Inventors:

- San Mateo CA, US
Robert V. TUOHY - Norristown PA, US
Stephen P. LEVINE - Norristown PA, US
Dana E. MOSESON - Norristown PA, US
Nicolas D. KIRKLAND - Norristown PA, US

Assignee:

THERAVIDA, INC. - San Mateo CA

International Classification:

A61K 9/20
A61K 31/4178

US Classification:

424465, 424464, 514397

Abstract:

Disclosed herein are pharmaceutical compositions comprising at least one minitablet, where the minitablet comprises a core, comprising pilocarpine, or a pharmaceutically acceptable salt thereof; and a coating layer comprising a coating polymer.