Andrew B. Sparks - Pikesville MD Noah Hoffman - Greensboro NC Brian K. Kay - Chapel Hill NC Dana M. Fowlkes - Chapel Hill NC Stephen J. McConnell - San Diego CA
Assignee:
University of North Carolina at Chapel Hill - Chapel Hill NC Cytogen Corp. - Princeton NJ
Novel polypeptides having functional domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
Polypeptides Having A Functional Domain Of Interest And Methods Of Identifying And Using Same
Andrew B. Sparks - Pikesville MD, US Noah Hoffman - Greensboro NC, US Brian K. Kay - Chapel Hill NC, US Dana M. Fowlkes - Chapel Hill NC, US Stephen J. McConnell - San Diego CA, US
Assignee:
Cytogen Corporation - Princeton NJ University of North Carolina at Chapel Hill - Chapel Hill NC
International Classification:
G01N 33/53
US Classification:
435 71, 435DIG 2, 435DIG 3
Abstract:
Novel polypeptides having functional domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
Polypeptides Having A Functional Domain Of Interest And Methods Of Identifying And Using Same
Andrew B. Sparks - Pikesville MD, US Noah Hoffman - Greensboro NC, US Brian K. Kay - Chapel Hill NC, US Dana M. Fowlkes - Chapel Hill NC, US Stephen J. McConnell - San Diego CA, US
International Classification:
C40B 30/04 G01N 33/566
US Classification:
506 9, 436501
Abstract:
Novel polypeptides having functional domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.
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Licenses:
Dist. of Columbia - Active 1989 Pennsylvania - Active 1997
Education:
University of Chicago Law School Degree - JD Graduated - 1985 Harvard University Degree - AB Graduated - 1981 Seton Hall Prep Graduated - 1977
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