Stephen W O'Connor

US Patent:

7166586, Jan 23, 2007

Filed:

Feb 26, 2003

Appl. No.:

10/374299

Inventors:

Stephen P. O'Connor - Newtown PA, US
Michael Lawrence - Yardley PA, US
Yan Shi - Flourtown PA, US
Philip D. Stein - Pennington NJ, US

Assignee:

Bristol Myers Squibb Co. - Princeton NJ

International Classification:

C07D 41/02
A61K 31/454
A61K 31/445

US Classification:

514183, 514349, 514326, 546207, 546218

Abstract:

Sulfonamide lactams of the following formula.

US Patent:

7420059, Sep 2, 2008

Filed:

Nov 15, 2004

Appl. No.:

10/989138

Inventors:

Stephen P. O'Connor - Lambertville NJ, US
Jeffrey Robl - Newtown PA, US
Yan Shi - Flourtown PA, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C07D 221/18
C07D 471/02
A61K 31/47

US Classification:

546 23, 546113, 514312

Abstract:

Compounds are provided having the following structureA method for treating the above diseases employing the above compounds is also provided.

US Patent:

7488725, Feb 10, 2009

Filed:

Oct 30, 2006

Appl. No.:

11/589409

Inventors:

Stephen P. O'Connor - Stockton NJ, US
Lawrence G. Hamann - North Grafton MA, US

Assignee:

Bristol-Myers Squibb Co. - Princeton NJ

International Classification:

C07D 207/06
C07D 207/14
C07D 401/06
C07D 403/06
C07D 413/06
A61K 31/40
A61K 31/422
A61K 31/4709
A61K 31/538
A61K 31/55
A61P 3/00

US Classification:

51421301, 5142305, 514312, 514343, 514378, 514414, 514423, 540593, 544105, 546165, 548247, 548468, 548540

Abstract:

Compounds are provided having the formula:.

US Patent:

7776347, Aug 17, 2010

Filed:

May 22, 2003

Appl. No.:

10/443394

Inventors:

Judith Lynne Kerschner - Hawthorne NJ, US
Stephen M. O'Connor - New York NY, US

Assignee:

Unilever Home & Personal Care USA, division of Conopco, Inc. - Greenwich CT

International Classification:

A61K 8/02
A61K 45/00

US Classification:

424401, 4242781

Abstract:

The present invention comprises a structured premix or “delivery vehicle” composition designed as a carrier to enhance the benefit (e. g. , via enhanced deposition or other mechanism) of a separate hydrophobic benefit agent(s) (for example, perfumes, skin lightening agents, etc. ), from personal product compositions (e. g. , liquid and bar cleansers, creams, emulsions, hair composition, deodorant etc. ). When the structured benefit agent composition is separately prepared and combined with the personal product composition (preferably while structured, premix composition is still in molten or liquid state), the personal product composition with structured benefit agent carrier provides enhanced deposition of the structured benefit agent and enhanced effect of the separate hydrophobic benefit agent(s) in or on the carrier or in the presence of structured benefit agent carrier.

US Patent:

7875582, Jan 25, 2011

Filed:

May 22, 2003

Appl. No.:

10/443569

Inventors:

Quynh Pham - Murray Hill NJ, US
Stephen M. O'Connor - New York NY, US
Alexander Lips - Edgewater NJ, US

Assignee:

Unilever Home & Personal Care USA, division of Conopco, Inc. - Greenwich CT

International Classification:

A61K 7/50

US Classification:

510141, 510152, 510153, 510155

Abstract:

The present invention relates to compositions comprising a structured benefit agent pre-mix or delivery vehicle comprising benefit agent structured with crystalline materials, as defined, which, when separately prepared and combined after preparation, provides enhanced delivery of benefit agent from a carrying composition into which the premix is added. The use of structured benefit agent also enhances delivery of separate benefit agents in the premix (which may or may not be structured) and of separate benefit agents added separately from the premix.

US Patent:

8092787, Jan 10, 2012

Filed:

May 22, 2003

Appl. No.:

10/443396

Inventors:

Xiaodong Zhang - Livingston NJ, US
Stephen M. O'Connor - New York NY, US
Pravin Shah - Rutherford NJ, US

Assignee:

Unilever Home & Personal Care USA, division of Conopco, Inc. - Greenwich CT

International Classification:

A61K 8/00
A61K 8/18
A61K 31/33
A61Q 5/00
A61Q 9/00
A01N 43/00

US Classification:

424 701, 514183

Abstract:

The present invention relates to compositions comprising a structured benefit agent pre-mix or delivery vehicle comprising benefit agent structured with crystalline materials, as defined, which when separately prepared and combined after preparation, provides enhanced delivery of optical modifier carried on, trapped within or in the presence of the structured benefit agent.

US Patent:

8415367, Apr 9, 2013

Filed:

Apr 6, 2011

Appl. No.:

13/080758

Inventors:

Dean Wacker - Hopewell NJ, US
Stephen O'Connor - Hopewell NJ, US
Zhenqiu Hong - Hopewell NJ, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

A01N 43/54
A61K 31/505

US Classification:

514275, 544331

Abstract:

Novel compounds of structure Formula I:.

US Patent:

8546394, Oct 1, 2013

Filed:

Apr 16, 2008

Appl. No.:

12/595524

Inventors:

Jun Li - Princeton NJ, US
James J. Li - Pennington NJ, US
Stephen P. O'Connor - Princeton NJ, US
Haixia Wang - Columbus NJ, US
Lawrence J. Kennedy - Titusville NJ, US
Jeffrey A. Robl - Newtown PA, US
Lawrence G. Hamann - North Grafton MA, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

A61K 31/495

US Classification:

514249, 544350

Abstract:

Novel compounds are provided which are 1 1-beta-hydroxysteroid dehydrogenase type I inhibitors. 1 1-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 1 1-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: W-L-Z or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W, L are defined herein and Z is selected from the following bicyclic heteroaryl groups: (a), (b), (c), (d).