Steve W Feng

US Patent:

20190316172, Oct 17, 2019

Filed:

Nov 29, 2017

Appl. No.:

16/464681

Inventors:

- Oakland CA, US
Omai Garner - Culver City CA, US
Dino Di Carlo - Los Angeles CA, US
Steve Wei Feng - Danville CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

C12Q 1/18
G01N 21/25
G06K 9/00
G06K 9/24

Abstract:

A method of performing antimicrobial susceptibility testing (AST) on a sample uses a reader device that mounts on a mobile phone having a camera. A microtiter plate containing wells preloaded with the bacteria-containing sample, growth medium, and drugs of differing concentrations is loaded into the reader device. The wells are illuminated using an array of illumination sources contained in the reader device. Images of the wells are acquired with the camera of the mobile phone. In one embodiment, the images are transmitted to a separate computing device for processing to classify each well as turbid or not turbid and generating MIC values and a susceptibility characterization for each drug in the panel based on the turbidity classification of the array of wells. The MIC values and the susceptibility characterizations for each drug are transmitted or returned to the mobile phone for display thereon.

US Patent:

20180196193, Jul 12, 2018

Filed:

Jun 17, 2016

Appl. No.:

15/737743

Inventors:

- Oakland CA, US
Brandon Berg - Chatsworth CA, US
Bingen Cortazar - Los Angeles CA, US
Derek Tseng - Buena Park CA, US
Steve Wei Feng - Danville CA, US
Haydar Ozkan - Los Angeles CA, US
Omai Garner - Culver City CA, US
Dino Di Carlo - Los Angeles CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

G02B 6/06
G01N 21/25
G06F 15/18
H04N 5/225

Abstract:

A micro-plate reader for use with a portable electronic device having a camera includes an opto-mechanical attachment configured to attach/detach to the portable electronic device and includes an array of illumination sources. A slot in the opto-mechanical attachment is dimensioned to receive an optically transparent plate containing an array of wells. Optical fibers are located in the opto-mechanical attachment and transmit light from each well to a reduced size header having, wherein the fiber array in the header has a cross-sectional area that is ≤10× the cross-sectional area of the wells in the plate. A lens located in the opto-mechanical attachment transmits light from the header fibers to the camera. Software executed on the portable electronic device or other computer is used to process the images to generate qualitative clinical determinations and/or quantitative index values for the separate wells.

US Patent:

20180003686, Jan 4, 2018

Filed:

Dec 21, 2015

Appl. No.:

15/538309

Inventors:

- Oakland CA, US
Bingen Cortazar - Los Angeles CA, US
Hatice Ceylan Koydemir - Los Angeles CA, US
Derek Tseng - Buena Park CA, US
Steve Feng - Danville CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

G01N 33/00
G01N 21/84
G06K 9/00
G06K 9/20
G06K 9/62
G01N 21/27
G01N 21/31
G06K 9/46
G06K 9/22
G01N 21/01

Abstract:

A system for measuring chlorophyll concentration in a leaf sample includes a leaf-holding illuminator device with a main body containing a power source, a plurality of switchable light sources emitting light at different spectra (e.g., red and white light from a broadband light source), and a cap detachably secured to the main body using one or more fastening means. The leaf sample is interposed between the main body and the cap and held in place during imaging. The system includes a mobile electronic device having a camera configured to capture an image of the leaf illuminated by the plurality of switchable light sources, the mobile electronic device having wireless connectivity to a network and an application contained therein configured to transfer the images to a remote sever or computer via the network for data processing. A final chlorophyll index value is calculated based on the transferred images.