Steven P Briggs

US Patent:

6455297, Sep 24, 2002

Filed:

Aug 7, 2001

Appl. No.:

09/923654

Inventors:

Gurmukh S. Johal - Johnston IA
Steven P. Briggs - Del Mar CA
John Gray - Toledo OH
Gongshe Hu - Albany CA

Assignee:

Pioneer Hi-Bred International, Inc. - Des Moines IA

International Classification:

C12N 988

US Classification:

435232, 435 691, 4352523, 4353201, 536 231, 536 232, 530300, 530350, 530376

Abstract:

Compositions and methods for enhancing disease resistance to a pathogen in a plant are provided. Methods of the invention comprise stably transforming a plant with an antisense nucleotide sequence for a gene encoding an enzyme in the C-5 porphyrin metabolic pathway and operably linking said antisense sequence to a pathogen-inducible promoter, such that invasion of a cell by a pathogen elicits a hypersensitive-like response that results in confinement of the pathogen to cells of initial contact. Transformed plants and seeds are provided. Nucleotide sequences encoding a wild-type maize urod gene useful in the present invention and the amino acid sequence for the protein encoded thereby are provided. These compositions are also useful for regulating cell death in specifically targeted tissues. A maize lesion mimic, dominant mutant phenotype, designated Les22, and the molecular basis for its manifestation are also provided.

US Patent:

6476292, Nov 5, 2002

Filed:

Feb 24, 1999

Appl. No.:

09/256898

Inventors:

Steven Briggs - Del Mar CA
Carl R. Simmons - Des Moines IA
John T. Tossberg - Des Moines IA

Assignee:

Pioneer Hi-Bred International, Inc. - Des Moines IA

International Classification:

A01H 500

US Classification:

800279, 800278, 800298, 800288, 800320, 8003201, 435 691, 4353201, 435419, 435468, 435430, 536 231, 536 237, 536 241

Abstract:

Compositions and methods for enhancing disease resistance in plants are provided. The method involves transforming a plant with an avirulence gene or alternatively with an avirulence gene and the complementing resistance gene. A pathogen inducible promoter or alternatively a weak constitutive promoter is used to control the desired level of disease control in the plant. Transformed plants, plant cells, tissues, and seed are also provided having enhanced disease resistance.

US Patent:

6479629, Nov 12, 2002

Filed:

Jun 18, 2001

Appl. No.:

09/883720

Inventors:

Donald Adelphi Baldwin - Des Moines IA
Steven P. Briggs - Del Mar CA
Virginia C. Crane - Des Moines CA

Assignee:

Pioneer Hi-Bred International, Inc. - Des Moines IA

International Classification:

A61K 3800

US Classification:

530324, 424 941, 536 232, 800279

Abstract:

Histone deacetylases and nucleotide sequences encoding said histone deacetylases are provided. The sequences as well as corresponding antisense constructs are useful for modulating gene activity in plants. Additionally, the sequences are useful for enhancing disease resistance in transformed plants.

US Patent:

6586657, Jul 1, 2003

Filed:

Jul 26, 2001

Appl. No.:

09/915674

Inventors:

Steven Briggs - Del Mar CA
Carl R. Simmons - Des Moines IA
John T. Tossberg - Des Moines IA

Assignee:

Pioneer Hi-Bred International, Inc. - Des Moines IA

International Classification:

A01H 500

US Classification:

800279, 800278, 800288, 800320, 8003201, 4353201, 435419, 435468, 435430, 536 237, 536 241

Abstract:

Compositions and methods for enhancing disease resistance in plants are provided. The method involves transforming a plant with an avirulence gene or alternatively with an avirulence gene and the complementing resistance gene. A pathogen inducible promoter or alternatively a weak constitutive promoter is used to control the desired level of disease control in the plant. Transformed plants, plant cells, tissues, and seed are also provided having enhanced disease resistance.

US Patent:

6599725, Jul 29, 2003

Filed:

Feb 2, 2001

Appl. No.:

09/776490

Inventors:

Steven P. Briggs - Des Moines IA
Gurmukh S. Johal - Columbia MO
John Gray - Cork City, IE

Assignee:

Pioneer Hi-Bred International, Inc. - Des Moines IA
Curators of the University of Missouri - Columbia MO

International Classification:

C12N 902

US Classification:

435189, 530350, 530370, 530372, 530376, 530379

Abstract:

The present invention is drawn to methods and compositions for suppressing cell death in plants. Specifically, novel proteins and genes are provided for use in plant transformation. The proteins and genes are useful for activating disease resistance, enhancing plant cell transformation efficiency, engineering herbicide resistance, genetically targeting cell ablations, and other methods involving the regulation of cell death in plants.

US Patent:

7041874, May 9, 2006

Filed:

Mar 19, 2002

Appl. No.:

10/101388

Inventors:

Gurmukh S. Johal - Urbandale IA, US
Dilbag S. Multani - Johnston IA, US
Steven P. Briggs - Del Mar CA, US

Assignee:

Pioneer Hi-Bred International, Inc. - Des Moines IA
The Curators of the University of Missouri - Columbia MO

International Classification:

C12N 15/29
C12N 15/82
A01H 5/00
A01H 5/10

US Classification:

800290, 800286, 800287, 800298, 536 236, 4353201, 435419

Abstract:

The invention relates to the genetic modification of plants, particularly to the expression of P-glycoprotein genes in transformed plants. Nucleotide sequences for the Br2 gene encoding a P-glycoprotein of maize and methods for their use are provided. The sequences find use in modifying the growth of plants.

US Patent:

7071307, Jul 4, 2006

Filed:

May 6, 2002

Appl. No.:

10/141531

Inventors:

Bipin K. Dalmia - San Diego CA, US
Steven P. Briggs - Del Mar CA, US
Greg del Val - San Diego CA, US
John R. Desjarlais - Pasadena CA, US
Peter Heifetz - San Diego CA, US
Peter Luginbuhl - San Diego CA, US
Umesh Muchhal - West Covina CA, US

Assignee:

Syngenta Participations AG - Basel
Xencor, Inc. - Monrovia CA

International Classification:

C07K 1/00

US Classification:

530350, 530300

Abstract:

The present invention relates to the use of a variety of methods for generating functional thioredoxin reductase variants in which at least one physical, chemical or biological property of the variant is altered in a specific and desired manner when compared to the wild-type protein.

US Patent:

7276584, Oct 2, 2007

Filed:

Jan 24, 2006

Appl. No.:

11/338199

Inventors:

Gurmukh S. Johal - West Lafayette IN, US
Dilbag S. Multani - Urbandale IA, US
Steven P. Briggs - Del Mar CA, US

International Classification:

C07K 1/00

US Classification:

530350

Abstract:

The invention relates to the genetic modification of plants, particularly to the expression of P-glycoprotein genes in transformed plants. Nucleotide sequences for the Br2 gene encoding a P-glycoprotein of maize and methods for their use are provided. The sequences find use in modifying the growth of plants.