Theodore Krontiris - Pasadena CA, US Garry Larson - San Dimas CA, US Steven Flanagan - Running Springs CA, US
Assignee:
CITY OF HOPE - DUARTE CA
International Classification:
C12Q001/68 C07H021/02 C07H021/04 C12P019/34
US Classification:
435/006000, 435/091100, 435/091200, 536/023100
Abstract:
Pathogenetic allele variants that predispose to a disease can be identified by stratifying affected sib pairs by allele-sharing statuss at two or more candidate loci. This locus stratification method has been used to identify an allelic variant at the ATM locus which is implicated in breast cancer.
Candidate Region Mismatch Scanning For Genotyping And Mutation Detection
Theodore Krontiris - Pasadena CA, US Martin Beaulieu - San Diego CA, US Steven Flanagan - Claremont CA, US
International Classification:
C12Q001/68 C12P019/34
US Classification:
435/006000, 435/091200
Abstract:
Use of the mismatch detection system, MutS, MutL and MutH, in PCR-based, automated, high-throughput genotyping and mutation detection of genomic DNA. Optimal sensitivity and signal-to-noise ratios are dependent upon monovalent cation concentration and MutL concentration. Strategies that can be easily adapted to automation for limiting the analysis to intersample heteroduplexes have been developed.
Theodore G. Krontiris - Pasadena CA Garry P. Larson - San Dimas CA Steven D. Flanagan - Running Springs CA
Assignee:
City of Hope - Duarte CA
International Classification:
C12Q 168 C12P 1934 C07H 2102 C07H 2104
US Classification:
435 6
Abstract:
Pathogenetic allele variants that predispose to a disease can be identified by stratifying affected sib pairs by allele-sharing statuss at two or more candidate loci. This locus stratification method has been used to identify an allelic variant at the ATM locus which is implicated in breast cancer.
Dr. Steven Flanagan, chair of Rehabilitation Medicine at NYU Langone Medical Center and an expert in traumatic brain injuries including concussions, said more attention needs to be paid to concussive injuries and identifying teens or other children with these injuries early.
Date: Jun 20, 2016
Category: Health
Source: Google
On overseas trip, Obama returns to his roots — in Ireland
Steven Flanagan, European affairs specialist with the Center for Strategic and International Studies, said the question for Obama on Afghanistan both in the U.S. and among allied leaders, is: "How will we begin the phased transition to Afghan lead in security affairs?"
Date: May 22, 2011
Category: U.S.
Source: Google
Bob Probert: Late NHL star among athletes hit by brain disease
"Chronic traumatic encephalopathy, or CTE, may be similar and may be seen in more and more athletes who play contact sports like football or ice hockey," Dr. Steven Flanagan, professor of rehabilitation medicine at New York University Langone Medical Center, wrote on brainline.org.