Compositions And Methods Using The Borreliacidal Epitope(S) Of Borrelia Burgdorferi Outer Surface Protein C (Ospc) For The Diagnosis And Prevention Of Lyme Disease
An OspC Dra fragment fusion peptide isolated from is described herein for the prevention, treatment and early diagnosis of Lyme disease in humans and other animals. This invention also relates to a screening method detecting anti-Osp borreliacidal antibody activity, and antibodies reacting with a protein fragment encoded by a DraI-SmaI DNA fragment of OspC.
Compositions And Methods Using The Borreliacidal Epitope(S) Of Borrelia Burgdorferi Outer Surface Protein C (Ospc) For The Diagnosis And Prevention Of Lyme Disease
Steven M. Callister - La Crosse WI Steven D. Lovrich - La Crosse WI Ronald F. Schell - Dade WI Dean A. Jobe - La Crosse WI
Assignee:
Gundersen Lutheran Medical Foundation - La Crosse WI
International Classification:
A61K 3902 A61K 4500 A61K 3900 A61K 3800 C07K 100
US Classification:
4241901
Abstract:
An OspC Dra fragment fusion peptide isolated from Borrelia burgdorferi is described herein for the prevention, treatment and early diagnosis of Lyme disease in humans and other animals. This invention also relates to a screening method detecting anti-Osp borreliacidal antibody activity, and antibodies reacting with a protein fragment encoded by a DraI-SmaI DNA fragment of OspC.
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Entrevista al Dr. Gustavo Lovrich
Es licenciado y doctor en Biologa de la Universidad de Buenos Aires. R...