Steven R Schwarz

US Patent:

56655762, Sep 9, 1997

Filed:

Jun 7, 1995

Appl. No.:

8/476286

Inventors:

Paul M. Cino - Bound Brook NJ
Steven R. Schwarz - Milltown NJ
Dana L. Cazzulino - New York NY

Assignee:

E. R. Squibb & Sons, Inc. - Princeton NJ

International Classification:

C12P 100
C12P 722
C12N 500

US Classification:

435156

Abstract:

A method for the production of taxanes such as taxol. The method includes inducing formation of callus cells by contacting an explant tissue with a liquid medium without complete submergence of the tissue in the medium. The callus cells formed are employed in a liquid suspension cell culture to produce one or more taxanes.

US Patent:

51601010, Nov 3, 1992

Filed:

Jun 5, 1991

Appl. No.:

7/711362

Inventors:

John R. Ferraro - Clinton CT
Philip P. Foerster - Waterbury CT
Peter T. Greenstreet - Sandy Hook CT
Steven R. Schwarz - Cranbury NJ
Milton R. Turgeon - Enfield CT

Assignee:

United Technologies, Corp. - Hartford CT

International Classification:

B64D 900

US Classification:

2441181

Abstract:

A buoy deployment system for an aircraft is disclosed which includes a multi-store gravity launching system which allows for discharge of different lengthsn and types of buoys. The gravity launch system includes a plurality of launch tubes, each including a spring biased door at the discharge end thereof, with the doors being either electrically actuated from the pilot cockpit via electrical controls, or, in the event of an electrical malfunction, being manually operable by an operator. Each buoy loaded therein is accessible for reconfiguration in flight, with each tube similarly being reloadable in flight. Also disclosed is a rotatable storage carousel including a plurality of semi-cylindrical tube section/latch assemblies, sized to restrain a plurality of buoys, which form storage stations on the carousel. The storage carousel maximizes the number and type of buoys which may be carried in a given space, being manually rotatable to allows access for setting the operational functions of the buoys contained therein. Utilizing the gravity launcher and storage carousel provides maximum mission flexibility while minimizing aircraft space requirements.

US Patent:

55277020, Jun 18, 1996

Filed:

Feb 23, 1994

Appl. No.:

8/202718

Inventors:

Paul M. Cino - Bound Brook NJ
Steven R. Schwarz - Milltown NJ
Dana L. Cazzulino - New York NY

Assignee:

E. R. Squibb & Sons, Inc. - Princeton NJ

International Classification:

C12N 500
C12P 1704

US Classification:

43524048

Abstract:

A method for the induction of callus cells capable of producing taxanes from explant tissue by partially submerging the explant tissue in a liquid culture medium on a membrane raft, resulting in callus formation. The induction of callus cells by this method provides direct transfer of the cells formed to a liquid medium for a suspension cell culture preparation of taxanes. Thus, there is no need of a separate growth or proliferation step in the method of this invention. Furthermore, callus cells can be produced by the method; and also disclosed is a method for the use of the callus cells so produced in a suspension cell culture preparation for taxanes.

US Patent:

48937673, Jan 16, 1990

Filed:

Jun 24, 1988

Appl. No.:

7/210960

Inventors:

John R. Ferraro - Clinton CT
Philip P. Foerster - Waterbury CT
Alan Rockall - Oxford CT
Steven R. Schwarz - Cranbury NJ

Assignee:

United Technologies Corporation - Hartford CT

International Classification:

B64C 122

US Classification:

2441181

Abstract:

A cable and equipment guide (35) for a helicopter (10) comprises a funnel (60) formed from a single thickness of malleable and polishable material, fixed to the helicopter fuselage (15) by a resilient mount comprising a bracket (120) carrying an elastomeric bushing (130) and a coil spring (70).

US Patent:

49627988, Oct 16, 1990

Filed:

Sep 28, 1988

Appl. No.:

7/250783

Inventors:

John R. Ferraro - Clinton CT
Philip P. Foerster - Waterbury CT
Peter T. Greenstreet - Sandy Hook CT
Steven R. Schwarz - Cranbury NJ
Milton R. Turgeon - Enfield CT

Assignee:

United Technologies Corporation - Hartford CT

International Classification:

B64D 110
B64D 112

US Classification:

2441371

Abstract:

A buoy deployment system for an aircraft is disclosed which includes a multi-store gravity launching system which allows for discharge of different lengths and types of buoys. The gravity launch system includes a plurality of launch tubes, each including a spring biased door at the discharge end thereof, with the doors being either electrically actuated from the pilot cockpit via electrical controls, or, in the event of an electrical malfunction, being manually operable by an operator. Each buoy loaded therein is accessible for reconfiguration in flight, with each tube similarly being reloadable in flight. Also disclosed is a rotatable storage carousel including a plurality of semi-cylindrical tube section/latch assemblies, sized to restrain a plurality of buoys, which form storage stations on the carousel. The storage carousel maximizes the number and type of buoys which may be carried in a given space, being manually rotatable to allows access for setting the operational functions of the buoys contained therein. Utilizing the gravity launcher and storage carousel provides maximum mission flexibility while minimizing aircraft space requirements.